Literature DB >> 17726442

Thinking inside the box. To cope with an increasing disease burden, drug discovery needs biologically relevant and predictive testing systems.

Lars E Sundstrom1.   

Abstract

Mesh：

Year:  2007        PMID： 17726442      PMCID： PMC3327535          DOI： 10.1038/sj.embor.7400939

Source DB:  PubMed          Journal:  EMBO Rep        ISSN： 1469-221X            Impact factor:   8.807


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  17 in total

1.  Drug discovery: a historical perspective.

Authors:  J Drews
Journal:  Science       Date:  2000-03-17       Impact factor: 47.728

2.  The price of innovation: new estimates of drug development costs.

Authors:  Joseph A DiMasi; Ronald W Hansen; Henry G Grabowski
Journal:  J Health Econ       Date:  2003-03       Impact factor: 3.883

3.  Is there a best strategy for drug discovery?

Authors:  Peter Warne; Clive Page
Journal:  Drug News Perspect       Date:  2003-04

4.  A return to the fundamentals of drug discovery?

Authors:  Michael Williams
Journal:  Curr Opin Investig Drugs       Date:  2004-01

5.  Molecular genetics: the Emperor's clothes of drug discovery?

Authors:  Gerry Higgs
Journal:  Drug Discov Today       Date:  2004-09-01       Impact factor: 7.851

6.  Cost of disorders of the brain in Europe.

Authors:  Patrik Andlin-Sobocki; Bengt Jönsson; Hans-Ulrich Wittchen; Jes Olesen
Journal:  Eur J Neurol       Date:  2005-06       Impact factor: 6.089

Review 7.  Organotypic cultures as tools for functional screening in the CNS.

Authors:  Lars Sundstrom; Barclay Morrison; Mark Bradley; Ashley Pringle
Journal:  Drug Discov Today       Date:  2005-07-15       Impact factor: 7.851

8.  The burden of brain diseases in Europe.

Authors:  J Olesen; M Leonardi
Journal:  Eur J Neurol       Date:  2003-09       Impact factor: 6.089

Review 9.  Pharmacological potential of embryonic stem cells.

Authors:  Thorsten Gorba; Timothy E Allsopp
Journal:  Pharmacol Res       Date:  2003-04       Impact factor: 7.658

Review 10.  Back to the future: the 'old-fashioned' way to new medications for neurodegeneration.

Authors:  Peter T Lansbury
Journal:  Nat Med       Date:  2004-07       Impact factor: 53.440
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  2 in total

1.  Why animal studies are often poor predictors of human reactions to exposure.

Authors:  Michael B Bracken
Journal:  J R Soc Med       Date:  2009-03       Impact factor: 5.344

2.  Identification of Psychoplastogenic N,N-Dimethylaminoisotryptamine (isoDMT) Analogues through Structure-Activity Relationship Studies.

Authors:  Lee E Dunlap; Arya Azinfar; Calvin Ly; Lindsay P Cameron; Jayashri Viswanathan; Robert J Tombari; Douglas Myers-Turnbull; Jack C Taylor; Ana Cristina Grodzki; Pamela J Lein; David Kokel; David E Olson
Journal:  J Med Chem       Date:  2020-01-24       Impact factor: 7.446
  2 in total

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