Literature DB >> 14983970

A return to the fundamentals of drug discovery?

Michael Williams.   

Abstract

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Year:  2004        PMID： 14983970

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN： 1472-4472


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  4 in total

1.  VeloceGenomics: an accelerated in vivo drug discovery approach to rapidly predict the biologic, drug-like activity of compounds, proteins, or genes.

Authors:  Ruben Papoian; Andreas Scherer; Muriel Saulnier; Frank Staedtler; André Cordier; Francois Legay; Gerard Maurer; Joerg Staeheli; Jacky Vonderscher; Salah-Dine Chibout
Journal:  Pharm Res       Date:  2005-09-22       Impact factor: 4.200

Review 2.  Thinking inside the box. To cope with an increasing disease burden, drug discovery needs biologically relevant and predictive testing systems.

Authors:  Lars E Sundstrom
Journal:  EMBO Rep       Date:  2007-07       Impact factor: 8.807

3.  Binding of NIR-conPK and NIR-6T to astrocytomas and microglial cells: evidence for a protein related to TSPO.

Authors:  Michelle Sexton; Grace Woodruff; Eiron Cudaback; Faith R Kreitzer; Cong Xu; Yi Hsing Lin; Thomas Möller; Mingfeng Bai; H Charles Manning; Darryl Bornhop; Nephi Stella
Journal:  PLoS One       Date:  2009-12-18       Impact factor: 3.240

4.  Identification of novel antimicrobials using a live-animal infection model.

Authors:  Terence I Moy; Anthony R Ball; Zafia Anklesaria; Gabriele Casadei; Kim Lewis; Frederick M Ausubel
Journal:  Proc Natl Acad Sci U S A       Date:  2006-06-26       Impact factor: 11.205
  4 in total

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