Literature DB >> 17720165

Ethnopharmacology and malaria: new hypothetical leads or old efficient antimalarials?

G Bourdy1, M L Willcox, H Ginsburg, Ph Rasoanaivo, B Graz, E Deharo.   

Abstract

New treatments are urgently needed to curb and eradicate malaria in developing countries. As most people living in malarial endemic areas use traditional medicine to fight this disease, why have new treatments not emerged recently from ethnopharmacology-oriented research? The rationale and limitations of the ethnopharmacological approach are discussed in this paper, focusing on ethnopharmacology methodologies and techniques used for assessing botanical samples for their antimalarial properties. Discrepancies often observed between strong ethnopharmacological reputation and laboratory results are discussed, as well as new research perspectives.

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Year:  2007        PMID: 17720165     DOI: 10.1016/j.ijpara.2007.07.004

Source DB:  PubMed          Journal:  Int J Parasitol        ISSN: 0020-7519            Impact factor:   3.981


  9 in total

1.  Antiplasmodial activity of aporphine alkaloids and sesquiterpene lactones from Liriodendron tulipifera L.

Authors:  Rocky Graziose; Thirumurugan Rathinasabapathy; Carmen Lategan; Alexander Poulev; Peter J Smith; Mary Grace; Mary Ann Lila; Ilya Raskin
Journal:  J Ethnopharmacol       Date:  2010-09-06       Impact factor: 4.360

2.  Genetic diversity of Plasmodium falciparum field isolates from south western Nigeria.

Authors:  G I Olasehinde; C S Yah; R Singh; O Olusola Ojuronbge; A A Ajayi; N Valecha; A O Abolaji; A O Adeyeba
Journal:  Afr Health Sci       Date:  2012-09       Impact factor: 0.927

3.  Ethnomedical survey of plants used by the Orang Asli in Kampung Bawong, Perak, West Malaysia.

Authors:  Anbu Jeba Sunilson John Samuel; Anandarajagopal Kalusalingam; Dinesh Kumar Chellappan; Rejitha Gopinath; Suraj Radhamani; Hj Azman Husain; Vignesh Muruganandham; Proom Promwichit
Journal:  J Ethnobiol Ethnomed       Date:  2010-02-07       Impact factor: 2.733

4.  Expanding the Antimalarial Drug Arsenal-Now, But How?

Authors:  Brian T Grimberg; Rajeev K Mehlotra
Journal:  Pharmaceuticals (Basel)       Date:  2011-05-01

Review 5.  Herbal Remedies Connected to Malaria like Fever in Iranian Ancient Medicinal Books- Brief Review Article.

Authors:  Azadeh Ghiaee; Farzaneh Naghibi; Somayeh Esmaeili; Mahmoud Mosaddegh
Journal:  Iran J Parasitol       Date:  2014 Oct-Dec       Impact factor: 1.012

6.  Aspidosperma pyrifolium, a medicinal plant from the Brazilian caatinga, displays a high antiplasmodial activity and low cytotoxicity.

Authors:  Isabela P Ceravolo; Carlos L Zani; Flávio J B Figueiredo; Markus Kohlhoff; Antônio E G Santana; Antoniana U Krettli
Journal:  Malar J       Date:  2018-11-26       Impact factor: 2.979

Review 7.  Malaria in South America: a drug discovery perspective.

Authors:  Luiza R Cruz; Thomas Spangenberg; Marcus V G Lacerda; Timothy N C Wells
Journal:  Malar J       Date:  2013-05-24       Impact factor: 2.979

8.  In vitro studies on the sensitivity pattern of Plasmodium falciparum to anti-malarial drugs and local herbal extracts.

Authors:  Grace I Olasehinde; Olusola Ojurongbe; Adegboyega O Adeyeba; Obasola E Fagade; Neena Valecha; Isaac O Ayanda; Adesola A Ajayi; Louis O Egwari
Journal:  Malar J       Date:  2014-02-20       Impact factor: 2.979

9.  Aspidosperma (Apocynaceae) plant cytotoxicity and activity towards malaria parasites. Part II: experimental studies withAspidosperma ramiflorum in vivo and in vitro.

Authors:  Anna C C Aguiar; Ananda C Cunha; Isabela Penna Ceravolo; Regina A Correia Gonçalves; Arildo J B Oliveira; Antoniana Ursine Krettli
Journal:  Mem Inst Oswaldo Cruz       Date:  2015-11       Impact factor: 2.743

  9 in total

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