OBJECTIVE: Carotid distensibility (CD) is a measure of carotid artery elasticity that has been introduced as a risk factor for cardiovascular disease. Information regarding reproducibility of sonographic CD measures is limited. The objective of this study was to evaluate the inter-reader reliability of sonographic measurements of common carotid artery (CCA) diameters and derived metrics of CD. METHODS: Two independent readers (R1 and R2) measured the systolic diameter (SD) and diastolic diameter (DD) for the right CCA from the B/M-mode sonographic registrations among 118 subjects. The derived CD metrics (strain, elastic modulus [E], stiffness [beta], and CD) were calculated. The inter-reader type 3 intraclass correlation coefficients (ICC3,1) for carotid diameters were calculated. RESULTS: The mean SDs +/- standard deviation were 7.15 +/- 1.43 mm for R1 and 7.24 +/- 1.43 mm for R2. The mean DDs were 6.71 +/- 1.36 mm for R1 and 6.68 +/- 1.41 mm for R2. The mean differences of SD and DD between R1 and R2 were 0.08 +/- 0.40 mm (paired t test, P = .04) and 0.03 +/- 0.43 mm (paired t test, P = .46), respectively. Inter-reader type 3 intraclass correlation coefficients were 0.96 for SD and 0.95 for DD. We observed a significant association of demographics with carotid diameters but not with derived CD metrics or risk factors. CONCLUSIONS: Our results suggest good reproducibility of CCA diameters measured with B/M-mode sonography. However, very small changes in linear measurements of carotid diameters can have big effects on estimates of arterial mechanical properties such as strain and Young's modulus. The standard boundary identification methods may not be precise and reproducible enough for use in a clinical setting.
OBJECTIVE: Carotid distensibility (CD) is a measure of carotid artery elasticity that has been introduced as a risk factor for cardiovascular disease. Information regarding reproducibility of sonographic CD measures is limited. The objective of this study was to evaluate the inter-reader reliability of sonographic measurements of common carotid artery (CCA) diameters and derived metrics of CD. METHODS: Two independent readers (R1 and R2) measured the systolic diameter (SD) and diastolic diameter (DD) for the right CCA from the B/M-mode sonographic registrations among 118 subjects. The derived CD metrics (strain, elastic modulus [E], stiffness [beta], and CD) were calculated. The inter-reader type 3 intraclass correlation coefficients (ICC3,1) for carotid diameters were calculated. RESULTS: The mean SDs +/- standard deviation were 7.15 +/- 1.43 mm for R1 and 7.24 +/- 1.43 mm for R2. The mean DDs were 6.71 +/- 1.36 mm for R1 and 6.68 +/- 1.41 mm for R2. The mean differences of SD and DD between R1 and R2 were 0.08 +/- 0.40 mm (paired t test, P = .04) and 0.03 +/- 0.43 mm (paired t test, P = .46), respectively. Inter-reader type 3 intraclass correlation coefficients were 0.96 for SD and 0.95 for DD. We observed a significant association of demographics with carotid diameters but not with derived CD metrics or risk factors. CONCLUSIONS: Our results suggest good reproducibility of CCA diameters measured with B/M-mode sonography. However, very small changes in linear measurements of carotid diameters can have big effects on estimates of arterial mechanical properties such as strain and Young's modulus. The standard boundary identification methods may not be precise and reproducible enough for use in a clinical setting.
Authors: Spyretta Golemati; Antonio Sassano; M John Lever; Anil A Bharath; Surinder Dhanjil; Andrew N Nicolaides Journal: Ultrasound Med Biol Date: 2003-03 Impact factor: 2.998
Authors: K H Schmitz; D K Arnett; A Bank; D Liao; G W Evans; K R Evenson; J Stevens; P Sorlie; A R Folsom Journal: Med Sci Sports Exerc Date: 2001-12 Impact factor: 5.411
Authors: Tanja Rundek; Mitchell S Elkind; John Pittman; Bernadette Boden-Albala; Steve Martin; Steve E Humphries; Suh-Hang Hank Juo; Ralph L Sacco Journal: Stroke Date: 2002-05 Impact factor: 7.914
Authors: Angelo Scuteri; Samer S Najjar; Denis C Muller; Reubin Andres; Hidetaka Hougaku; E Jeffrey Metter; Edward G Lakatta Journal: J Am Coll Cardiol Date: 2004-04-21 Impact factor: 24.094
Authors: Diane E Bild; David A Bluemke; Gregory L Burke; Robert Detrano; Ana V Diez Roux; Aaron R Folsom; Philip Greenland; David R Jacob; Richard Kronmal; Kiang Liu; Jennifer Clark Nelson; Daniel O'Leary; Mohammed F Saad; Steven Shea; Moyses Szklo; Russell P Tracy Journal: Am J Epidemiol Date: 2002-11-01 Impact factor: 4.897
Authors: Allen R Yu; Bima Hasjim; Luke E Yu; Christopher Gabriel; Alexander Anshus; Jonathan B Lee; Michael J Louthan; Esther C Kim; Katrina Lee; Christina Tse; Thomas Keown; Shadi Lahham; Maili Alvarado; Steven Bunch; Abdulatif Gari; J Christian Fox Journal: World J Emerg Med Date: 2017
Authors: Tadashi Araki; P Krishna Kumar; Harman S Suri; Nobutaka Ikeda; Ajay Gupta; Luca Saba; Jeny Rajan; Francesco Lavra; Aditya M Sharma; Shoaib Shafique; Andrew Nicolaides; John R Laird; Jasjit S Suri Journal: J Med Syst Date: 2016-06-14 Impact factor: 4.460
Authors: Zhehao Hu; Anthony G Christodoulou; Nan Wang; Jaime L Shaw; Shlee S Song; Marcel M Maya; Mariko L Ishimori; Lindsy J Forbess; Jiayu Xiao; Xiaoming Bi; Fei Han; Debiao Li; Zhaoyang Fan Journal: Magn Reson Med Date: 2020-04-16 Impact factor: 4.668
Authors: M D Walker; J Fleischer; T Rundek; D J McMahon; S Homma; R Sacco; S J Silverberg Journal: J Clin Endocrinol Metab Date: 2009-09-15 Impact factor: 5.958