Literature DB >> 17707636

A mechanism for active hearing.

Tianying Ren1, Peter G Gillespie.   

Abstract

The remarkable sensitivity, frequency selectivity, and nonlinearity of the cochlea have been attributed to the putative 'cochlear amplifier', which consumes metabolic energy to amplify the cochlear mechanical response to sounds. Recent studies have demonstrated that outer hair cells actively generate force using somatic electromotility and active hair-bundle motion. However, the expected power gain of the cochlear amplifier has not been demonstrated experimentally, and the measured location of cochlear nonlinearity is inconsistent with the predicted location of the cochlear amplifier. We instead propose a 'cochlear transformer' mechanism to interpret cochlear performance.

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Year:  2007        PMID: 17707636      PMCID: PMC2259439          DOI: 10.1016/j.conb.2007.07.013

Source DB:  PubMed          Journal:  Curr Opin Neurobiol        ISSN: 0959-4388            Impact factor:   6.627


  63 in total

1.  The mechanical waveform of the basilar membrane. III. Intensity effects.

Authors:  E de Boer; A L Nuttall
Journal:  J Acoust Soc Am       Date:  2000-03       Impact factor: 1.840

2.  The mechanical waveform of the basilar membrane. II. From data to models--and back.

Authors:  E de Boer; A L Nuttall
Journal:  J Acoust Soc Am       Date:  2000-03       Impact factor: 1.840

3.  Mechanoelectrical transduction of adult outer hair cells studied in a gerbil hemicochlea.

Authors:  David Z Z He; Shuping Jia; Peter Dallos
Journal:  Nature       Date:  2004-06-17       Impact factor: 49.962

4.  Otoacoustic emissions without somatic motility: can stereocilia mechanics drive the mammalian cochlea?

Authors:  M C Liberman; Jian Zuo; J J Guinan
Journal:  J Acoust Soc Am       Date:  2004-09       Impact factor: 1.840

5.  Prestin is the motor protein of cochlear outer hair cells.

Authors:  J Zheng; W Shen; D Z He; K B Long; L D Madison; P Dallos
Journal:  Nature       Date:  2000-05-11       Impact factor: 49.962

Review 6.  Hair cell based amplification in the cochlea.

Authors:  J F Ashmore; P J Kolston
Journal:  Curr Opin Neurobiol       Date:  1994-08       Impact factor: 6.627

7.  Alternating current delivered into the scala media alters sound pressure at the eardrum.

Authors:  A E Hubbard; D C Mountain
Journal:  Science       Date:  1983-11-04       Impact factor: 47.728

8.  An active process in cochlear mechanics.

Authors:  H Davis
Journal:  Hear Res       Date:  1983-01       Impact factor: 3.208

9.  Stimulated acoustic emissions from within the human auditory system.

Authors:  D T Kemp
Journal:  J Acoust Soc Am       Date:  1978-11       Impact factor: 1.840

Review 10.  Active hair bundle movements and the cochlear amplifier.

Authors:  Anthony Ricci
Journal:  J Am Acad Audiol       Date:  2003-08       Impact factor: 1.664

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  11 in total

1.  Plasticity in membrane cholesterol contributes toward electrical maturation of hearing.

Authors:  Snezana Levic; Ebenezer N Yamoah
Journal:  J Biol Chem       Date:  2010-12-16       Impact factor: 5.157

Review 2.  Primary processes in sensory cells: current advances.

Authors:  Stephan Frings
Journal:  J Comp Physiol A Neuroethol Sens Neural Behav Physiol       Date:  2008-11-15       Impact factor: 1.836

Review 3.  Silencing the cochlear amplifier by immobilizing prestin.

Authors:  Ulrich Müller; Peter Gillespie
Journal:  Neuron       Date:  2008-05-08       Impact factor: 17.173

4.  Measurement of cochlear power gain in the sensitive gerbil ear.

Authors:  Tianying Ren; Wenxuan He; Peter G Gillespie
Journal:  Nat Commun       Date:  2011       Impact factor: 14.919

5.  Active touch sensing.

Authors:  Tony J Prescott; Mathew E Diamond; Alan M Wing
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-11-12       Impact factor: 6.237

6.  Distribution of frequencies of spontaneous oscillations in hair cells of the bullfrog sacculus.

Authors:  D Ramunno-Johnson; C E Strimbu; L Fredrickson; K Arisaka; D Bozovic
Journal:  Biophys J       Date:  2009-02       Impact factor: 4.033

Review 7.  Human hereditary hearing impairment: mouse models can help to solve the puzzle.

Authors:  Karen Vrijens; Lut Van Laer; Guy Van Camp
Journal:  Hum Genet       Date:  2008-09-11       Impact factor: 4.132

8.  The hearing gene Prestin reunites echolocating bats.

Authors:  Gang Li; Jinhong Wang; Stephen J Rossiter; Gareth Jones; James A Cotton; Shuyi Zhang
Journal:  Proc Natl Acad Sci U S A       Date:  2008-09-05       Impact factor: 11.205

9.  Energy Flux in the Cochlea: Evidence Against Power Amplification of the Traveling Wave.

Authors:  Marcel van der Heijden; Corstiaen P C Versteegh
Journal:  J Assoc Res Otolaryngol       Date:  2015-07-07

10.  Effects of Stimulus Intensity on Low-Frequency Toneburst Cochlear Microphonic Waveforms.

Authors:  Ming Zhang
Journal:  Audiol Res       Date:  2013-02-21
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