Literature DB >> 17705204

Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste.

Karen Köhler1, Alexander Hillebrecht, Johannes Schulze Wischeler, Alessio Innocenti, Andreas Heine, Claudiu T Supuran, Gerhard Klebe.   

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Year:  2007        PMID： 17705204     DOI： 10.1002/anie.200701189

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  31 in total

Review 1.  Carbonic anhydrase as a model for biophysical and physical-organic studies of proteins and protein-ligand binding.

Authors:  Vijay M Krishnamurthy; George K Kaufman; Adam R Urbach; Irina Gitlin; Katherine L Gudiksen; Douglas B Weibel; George M Whitesides
Journal:  Chem Rev       Date:  2008-03       Impact factor: 60.622

2.  Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclization/deprotection strategy.

Authors:  Akilah B Murray; Marta Quadri; Haoxi Li; Robert McKenna; Nicole A Horenstein
Journal:  Carbohydr Res       Date:  2019-03-19       Impact factor: 2.104

3.  2-Chloro-N-(4-sulfamoylphen-yl)acetamide.

Authors:  Mehmet Akkurt; Serife Pınar Yalçın; Hasan Türkmen; Orhan Büyükgüngör
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-06-05

4.  Saccharin: a lead compound for structure-based drug design of carbonic anhydrase IX inhibitors.

Authors:  Brian P Mahon; Alex M Hendon; Jenna M Driscoll; Gregory M Rankin; Sally-Ann Poulsen; Claudiu T Supuran; Robert McKenna
Journal:  Bioorg Med Chem       Date:  2014-12-23       Impact factor: 3.641

5.  Insights towards sulfonamide drug specificity in α-carbonic anhydrases.

Authors:  Mayank Aggarwal; Bhargav Kondeti; Robert McKenna
Journal:  Bioorg Med Chem       Date:  2012-08-28       Impact factor: 3.641

6.  Response to Perspectives on the Classical Enzyme Carbonic Anhydrase and the Search for Inhibitors.

Authors:  Andrea Angeli; Fabrizio Carta; Alessio Nocentini; Jean-Yves Winum; Raivis Zalubovskis; Valentina Onnis; Wagdy M Eldehna; Clemente Capasso; Simone Carradori; William A Donald; Shoukat Dedhar; Claudiu T Supuran
Journal:  Biophys J       Date:  2020-12-08       Impact factor: 4.033

7.  Saccharin sulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII.

Authors:  Vaida Morkūnaitė; Lina Baranauskienė; Asta Zubrienė; Visvaldas Kairys; Jekaterina Ivanova; Pēteris Trapencieris; Daumantas Matulis
Journal:  Biomed Res Int       Date:  2014-09-03       Impact factor: 3.411

8.  A class of carbonic anhydrase I - selective activators.

Authors:  Erol Licsandru; Muhammet Tanc; Istvan Kocsis; Mihail Barboiu; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2016-11-01       Impact factor: 5.051

9.  Synthesis of Novel Saccharin Derivatives.

Authors:  Gregory M Rankin; Sally-Ann Poulsen
Journal:  Molecules       Date:  2017-03-23       Impact factor: 4.411

10.  Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX.

Authors:  Aikaterini Peperidou; Silvia Bua; Murat Bozdag; Dimitra Hadjipavlou-Litina; Claudiu T Supuran
Journal:  Molecules       Date:  2018-01-12       Impact factor: 4.411
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