Literature DB >> 17703706

Experiences of gamma hydroxybutyrate (GHB) ingestion: a focus group study.

Judith C Barker1, Shana L Harris, Jo E Dyer.   

Abstract

GHB (gamma hydroxybutyrate) is a significant new drug of abuse added to the United States Controlled Substance Act in 2000. The majority of the published literature on GHB consists of clinical case reports, mainly from emergency departments, and a collection of laboratory-based studies, focused mainly on anesthesia. While comments about the various experiences and behaviors of human users are often included in such studies or reports, these aspects of GHB are only just beginning to be systematically investigated or detailed. Reported here are data from a qualitative study using focus group methods on the consumption habits, experiences, and beliefs of GHB users. A total of 51 people, 30 men and 21 women, mean age of 31.1+/-7.6 years (range 18 to 52 years), who report having used GHB for an average of 4.3+/-2.5 years (range one to 11 years), were interviewed in 10 separate groups held in 2004. This article discusses broadly the general experience of the GHB high, major perceived benefits including sexual responses to the drug, perceived risks and dangers of ingestion, co-ingestion, and various contexts of use. It concludes with a discussion of the implications drawn from this information for clinicians treating patients who use GHB.

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Year:  2007        PMID: 17703706      PMCID: PMC2257870          DOI: 10.1080/02791072.2007.10399870

Source DB:  PubMed          Journal:  J Psychoactive Drugs        ISSN: 0279-1072


  25 in total

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Authors:  A R Winstock; P Griffiths; D Stewart
Journal:  Drug Alcohol Depend       Date:  2001-09-01       Impact factor: 4.492

2.  Adverse events, including death, associated with the use of 1,4-butanediol.

Authors:  D L Zvosec; S W Smith; J R McCutcheon; J Spillane; B J Hall; E A Peacock
Journal:  N Engl J Med       Date:  2001-01-11       Impact factor: 91.245

3.  A qualitative analysis of GHB use among gay men: Reasons for use despite potential adverse outcomes.

Authors:  Joseph J Palamar; Perry N Halkitis
Journal:  Int J Drug Policy       Date:  2006-01-01

4.  The Circuit Party Men's Health Survey: findings and implications for gay and bisexual men.

Authors:  G Mansergh; G N Colfax; G Marks; M Rader; R Guzman; S Buchbinder
Journal:  Am J Public Health       Date:  2001-06       Impact factor: 9.308

Review 5.  Developments in the epidemiology of drug use and drug use disorders.

Authors:  Wilson M Compton; Yonette F Thomas; Kevin P Conway; James D Colliver
Journal:  Am J Psychiatry       Date:  2005-08       Impact factor: 18.112

6.  Circuit party attendance, club drug use, and unsafe sex in gay men.

Authors:  A M Mattison; M W Ross; T Wolfson; D Franklin
Journal:  J Subst Abuse       Date:  2001

7.  The use of amphetamine in gamma-hydroxybutyrate overdose: a case report.

Authors:  Francis P Kohrs; Christopher Mann; Ryan Greenberg
Journal:  J Psychoactive Drugs       Date:  2004-09

8.  Clinical course of gamma-hydroxybutyrate overdose.

Authors:  R L Chin; K A Sporer; B Cullison; J E Dyer; T D Wu
Journal:  Ann Emerg Med       Date:  1998-06       Impact factor: 5.721

9.  Use of GHB compounds by HIV-positive individuals.

Authors:  Alvaro Camacho; Scott C Matthews; Joel E Dimsdale
Journal:  Am J Addict       Date:  2004 Mar-Apr

10.  GHB use among Australians: characteristics, use patterns and associated harm.

Authors:  Louisa Degenhardt; Shane Darke; Paul Dillon
Journal:  Drug Alcohol Depend       Date:  2002-06-01       Impact factor: 4.492

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  20 in total

1.  Behavioral effects of gamma-hydroxybutyrate in humans.

Authors:  Alison Oliveto; William Brooks Gentry; Rhonda Pruzinsky; Kishorchandra Gonsai; Thomas R Kosten; Bridget Martell; James Poling
Journal:  Behav Pharmacol       Date:  2010-07       Impact factor: 2.293

Review 2.  Pharmacological Treatment in γ-Hydroxybutyrate (GHB) and γ-Butyrolactone (GBL) Dependence: Detoxification and Relapse Prevention.

Authors:  Rama M Kamal; Martijn S van Noorden; Wim Wannet; Harmen Beurmanjer; Boukje A G Dijkstra; Arnt Schellekens
Journal:  CNS Drugs       Date:  2017-01       Impact factor: 5.749

3.  A web-based study of gamma hydroxybutyrate (GHB): patterns, experiences, and functions of use.

Authors:  L A R Stein; Rebecca Lebeau; Mary Clair; Rosemarie Martin; Monte Bryant; Susan Storti; Peter Monti
Journal:  Am J Addict       Date:  2010-11-12

4.  Effects of gamma-hydroxybutyric acid on spatial learning and memory in adolescent and adult female rats.

Authors:  Ratna Sircar; Ashim Basak; Debashish Sircar; Li-Cheng Wu
Journal:  Pharmacol Biochem Behav       Date:  2010-05-09       Impact factor: 3.533

5.  Gamma-Hydroxybutyrate Increases Resting-State Limbic Perfusion and Body and Emotion Awareness in Humans.

Authors:  Oliver G Bosch; Fabrizio Esposito; Michael M Havranek; Dario Dornbierer; Robin von Rotz; Philipp Staempfli; Boris B Quednow; Erich Seifritz
Journal:  Neuropsychopharmacology       Date:  2017-05-31       Impact factor: 7.853

6.  Physical dependence on gamma-hydroxybutrate (GHB) prodrug 1,4-butanediol (1,4-BD): time course and severity of withdrawal in baboons.

Authors:  Amy K Goodwin; K Michael Gibson; Elise M Weerts
Journal:  Drug Alcohol Depend       Date:  2013-03-26       Impact factor: 4.492

7.  Area-level socioeconomic status in relation to outcomes in gamma-hydroxybutyrate intoxication.

Authors:  Ilene B Anderson; Susan Y Kim-Katz; Jo Ellen Dyer; Gillian E Earnest; John P Lamb; Paul D Blanc
Journal:  Clin Toxicol (Phila)       Date:  2009-01       Impact factor: 4.467

Review 8.  Illicit gamma-hydroxybutyrate (GHB) and pharmaceutical sodium oxybate (Xyrem): differences in characteristics and misuse.

Authors:  Lawrence P Carter; Daniel Pardi; Jane Gorsline; Roland R Griffiths
Journal:  Drug Alcohol Depend       Date:  2009-06-02       Impact factor: 4.492

9.  Systematic assessment of gamma hydroxybutyrate (GHB) effects during and after acute intoxication.

Authors:  Susan Y Kim; Judith C Barker; Ilene B Anderson; Jo Ellen Dyer; Gillian Earnest; Paul D Blanc
Journal:  Am J Addict       Date:  2008 Jul-Aug

Review 10.  Behavioral analyses of GHB: receptor mechanisms.

Authors:  Lawrence P Carter; Wouter Koek; Charles P France
Journal:  Pharmacol Ther       Date:  2008-10-29       Impact factor: 12.310

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