Literature DB >> 21175918

A web-based study of gamma hydroxybutyrate (GHB): patterns, experiences, and functions of use.

L A R Stein1, Rebecca Lebeau, Mary Clair, Rosemarie Martin, Monte Bryant, Susan Storti, Peter Monti.   

Abstract

GHB (gamma hydroxybutyrate) was developed as a general anesthetic. Due to dosing difficulty and side effects, regular use was discontinued. Medical uses include treating sleep and alcohol disorders. In the 1990s, it was promoted as a supplement and taken to improve mood and sex. GHB and its analogs (gamma butyrolactone and butanediol) were widely available until federal regulations were put into effect with mounting evidence of adverse events. This survey (N = 61) study was conducted to assess patterns, experiences, and functions of use. Much of what is understood regarding GHB treatment is based on hospital case studies for overdose and withdrawal. Not enough is known about prevention, reducing use and associated problems, or relapse. We know little about specific drug effect expectancies, triggers, coping skills, and consequences of use (positive/negative). While the drug treatment literature has a wealth of information to draw upon, GHB-specific information may greatly assist relapse prevention. American Academy of Addiction Psychiatry.

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Year:  2010        PMID: 21175918      PMCID: PMC3065821          DOI: 10.1111/j.1521-0391.2010.00099.x

Source DB:  PubMed          Journal:  Am J Addict        ISSN: 1055-0496


  23 in total

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Authors:  Elizabeth T Miller; Dan J Neal; Lisa J Roberts; John S Baer; Sally O Cressler; Jane Metrik; G Alan Marlatt
Journal:  Psychol Addict Behav       Date:  2002-03

2.  Gamma-hydroxybutyric acid versus naltrexone in maintaining alcohol abstinence: an open randomized comparative study.

Authors:  F Caputo; G Addolorato; F Lorenzini; M Domenicali; G Greco; A del RE; G Gasbarrini; G F Stefanini; M Bernardi
Journal:  Drug Alcohol Depend       Date:  2003-05-01       Impact factor: 4.492

3.  Stages and processes of self-change of smoking: toward an integrative model of change.

Authors:  J O Prochaska; C C DiClemente
Journal:  J Consult Clin Psychol       Date:  1983-06

4.  An instrument for measuring coping behaviours in hospitalized alcoholics: implications for relapse prevention treatment.

Authors:  G K Litman; J Stapleton; A N Oppenheim; M Peleg
Journal:  Br J Addict       Date:  1983-09

5.  Gamma-hydroxybutyric acid: patterns of use, effects and withdrawal.

Authors:  K Miotto; J Darakjian; J Basch; S Murray; J Zogg; R Rawson
Journal:  Am J Addict       Date:  2001

6.  Use, function, and subjective experiences of gamma-hydroxybutyrate (GHB).

Authors:  Harry R Sumnall; Kerry Woolfall; Sara Edwards; Jon C Cole; Caryl M Beynon
Journal:  Drug Alcohol Depend       Date:  2007-09-04       Impact factor: 4.492

Review 7.  Illicit gamma-hydroxybutyrate (GHB) and pharmaceutical sodium oxybate (Xyrem): differences in characteristics and misuse.

Authors:  Lawrence P Carter; Daniel Pardi; Jane Gorsline; Roland R Griffiths
Journal:  Drug Alcohol Depend       Date:  2009-06-02       Impact factor: 4.492

8.  A factor analysis of the important people inventory.

Authors:  David R Groh; Bradley D Olson; Leonard A Jason; Margaret I Davis; Joseph R Ferrari
Journal:  Alcohol Alcohol       Date:  2007-05-17       Impact factor: 2.826

9.  Assessing consequences of substance use: psychometric properties of the inventory of drug use consequences.

Authors:  Kimberly A Blanchard; Jon Morgenstern; Thomas J Morgan; Erich W Lobouvie; Donald A Bux
Journal:  Psychol Addict Behav       Date:  2003-12

10.  Gamma hydroxybutyrate: an ethnographic study of recreational use and abuse.

Authors:  Steven J Lee; Petros Levounis
Journal:  J Psychoactive Drugs       Date:  2008-09
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  5 in total

Review 1.  Pharmacological Treatment in γ-Hydroxybutyrate (GHB) and γ-Butyrolactone (GBL) Dependence: Detoxification and Relapse Prevention.

Authors:  Rama M Kamal; Martijn S van Noorden; Wim Wannet; Harmen Beurmanjer; Boukje A G Dijkstra; Arnt Schellekens
Journal:  CNS Drugs       Date:  2017-01       Impact factor: 5.749

2.  Comparative abuse liability of GHB and ethanol in humans.

Authors:  Matthew W Johnson; Roland R Griffiths
Journal:  Exp Clin Psychopharmacol       Date:  2013-02-18       Impact factor: 3.157

3.  Self-administration of gamma-hydroxybutyric acid (GHB) precursors gamma-butyrolactone (GBL) and 1,4-butanediol (1,4-BD) in baboons.

Authors:  Amy K Goodwin; Barbara J Kaminski; Elise M Weerts
Journal:  Psychopharmacology (Berl)       Date:  2012-09-04       Impact factor: 4.530

4.  Baclofen as relapse prevention in the treatment of Gamma- Hydroxybutyrate (GHB) dependence: an open label study.

Authors:  Rama M Kamal; Arnt Schellekens; Cornelis A J De Jong; Boukje A G Dijkstra
Journal:  BMC Psychiatry       Date:  2015-04-28       Impact factor: 3.630

5.  Symptoms and signs in interpreting gamma-hydroxybutyrate (GHB) intoxication - an explorative study.

Authors:  Margareta Warrén Stomberg; Kai Knudsen; Henrik Stomberg; Ingela Skärsäter
Journal:  Scand J Trauma Resusc Emerg Med       Date:  2014-04-23       Impact factor: 2.953

  5 in total

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