Literature DB >> 17685618

Thermodynamics of phosphopeptide tethering to BRCT: the structural minima for inhibitor design.

G L Lokesh1, B K Muralidhara, Surendra S Negi, Amarnath Natarajan.   

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Year:  2007        PMID: 17685618     DOI: 10.1021/ja0739178

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


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  18 in total

Review 1.  BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies.

Authors:  Seth M Dever; E Railey White; Matthew C T Hartman; Kristoffer Valerie
Journal:  Cell Cycle       Date:  2012-02-15       Impact factor: 4.534

Review 2.  Small molecule adenosine 5'-monophosphate activated protein kinase (AMPK) modulators and human diseases.

Authors:  Sandeep Rana; Elizabeth C Blowers; Amarnath Natarajan
Journal:  J Med Chem       Date:  2014-08-28       Impact factor: 7.446

3.  Structure-activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1.

Authors:  Ziyan Yuan; Eric A Kumar; Smitha Kizhake; Amarnath Natarajan
Journal:  J Med Chem       Date:  2011-05-26       Impact factor: 7.446

4.  Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design.

Authors:  Ziyan Yuan; Eric A Kumar; Stephen J Campbell; Nicholas Y Palermo; Smitha Kizhake; J N Mark Glover; Amarnath Natarajan
Journal:  ACS Med Chem Lett       Date:  2011-10-13       Impact factor: 4.345

5.  Computational and experimental studies of the interaction between phospho-peptides and the C-terminal domain of BRCA1.

Authors:  Victor M Anisimov; Arturas Ziemys; Smitha Kizhake; Ziyan Yuan; Amarnath Natarajan; Claudio N Cavasotto
Journal:  J Comput Aided Mol Des       Date:  2011-11-16       Impact factor: 3.686

6.  Synthesis of unnatural amino acid derivatives via palladium catalyzed 1,4 addition of boronic acids.

Authors:  Devalina Ray; Abijah M Nyong; Amarnath Natarajan
Journal:  Tetrahedron Lett       Date:  2010-05-12       Impact factor: 2.415

7.  Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction.

Authors:  Anton Simeonov; Adam Yasgar; Ajit Jadhav; G L Lokesh; Carleen Klumpp; Sam Michael; Christopher P Austin; Amarnath Natarajan; James Inglese
Journal:  Anal Biochem       Date:  2007-12-05       Impact factor: 3.365

8.  Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites.

Authors:  Paris R Watson; Timothy W Craven; Xinting Li; Stephen Rettie; Parisa Hosseinzadeh; Fátima Pardo-Avila; Asim K Bera; Vikram Khipple Mulligan; Peilong Lu; Alexander S Ford; Brian D Weitzner; Lance J Stewart; Adam P Moyer; Maddalena Di Piazza; Joshua G Whalen; Per Jr Greisen; David W Christianson; David Baker
Journal:  Nat Commun       Date:  2021-06-07       Impact factor: 14.919

Review 9.  Structural mechanisms underlying signaling in the cellular response to DNA double strand breaks.

Authors:  Inbal Mermershtain; J N Mark Glover
Journal:  Mutat Res       Date:  2013-07-27       Impact factor: 2.433

10.  Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations.

Authors:  Yves Nominé; Maria Victoria Botuyan; Zeljko Bajzer; Whyte G Owen; Ariel J Caride; Emeric Wasielewski; Georges Mer
Journal:  Biochemistry       Date:  2008-08-22       Impact factor: 3.162

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