Literature DB >> 17666242

U.S. Phase I preliminary results of use of the Otologics MET Fully-Implantable Ossicular Stimulator.

Herman A Jenkins1, James S Atkins, Drew Horlbeck, Michael E Hoffer, Ben Balough, Joseph V Arigo, George Alexiades, William Garvis.   

Abstract

OBJECTIVES: The safety of the Otologics Fully-Implantable MET Ossicular Stimulator was assessed in adult patients with bilateral moderate to severe sensorineural hearing loss.
METHODS: Surgical implantation of the ossicular stimulator was performed. A repeated-measure, within-subjects design assessed safety and aided sound field thresholds and speech performances with the subject's own, appropriately fitted, walk-in hearing aid(s) and the Otologics Fully-Implantable MET Ossicular Stimulator.
RESULTS: Twenty patients were implanted and activated as part of the Phase I clinical trial. Results demonstrated 10-20 dB of functional gain across audiometric frequencies. Pure tone averages and monaural word recognition scores were slightly better for the walk-in-aided condition, while patient benefit scales favored the postoperative implant-aided conditions. CONCLUSION/SIGNIFICANCE: Although monaural word scores and aided thresholds favored the walk-in-aided condition, preliminary results indicate that the Otologics MET Fully-Implantable Ossicular Stimulator is an alternative to currently available hearing aids in patients with sensorineural hearing loss.

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Mesh:

Year:  2007        PMID: 17666242     DOI: 10.1016/j.otohns.2007.03.012

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   3.497


  21 in total

1.  Controlling the position and the dislocation of the middle ear transducer with high-resolution computed tomography and digital volume tomography: implications for the transducers' design.

Authors:  Georgios Kontorinis; Anja M Giesemann; Thomas Witt; Friedrich Goetz; Burkard Schwab
Journal:  Eur Arch Otorhinolaryngol       Date:  2011-09-22       Impact factor: 2.503

Review 2.  [Semi-implantable hearing aids for sensorineural hearing loss and combined hearing loss: experiences at the German Armed Forces Hospital in Ulm].

Authors:  M Tisch; H Maier
Journal:  HNO       Date:  2009-03       Impact factor: 1.284

3.  Round window membrane implantation with an active middle ear implant: a study of the effects on the performance of round window exposure and transducer tip diameter in human cadaveric temporal bones.

Authors:  Stéphane Tringali; Kanthaiah Koka; Arnaud Deveze; N Julian Holland; Herman A Jenkins; Daniel J Tollin
Journal:  Audiol Neurootol       Date:  2010-02-11       Impact factor: 1.854

4.  Air- and Bone-Conducted Sources of Feedback With an Active Middle Ear Implant.

Authors:  Renee M Banakis Hartl; James R Easter; Mohamed A Alhussaini; Daniel J Tollin; Herman A Jenkins
Journal:  Ear Hear       Date:  2019 May/Jun       Impact factor: 3.570

5.  Comparisons of electromagnetic and piezoelectric floating-mass transducers in human cadaveric temporal bones.

Authors:  Il-Yong Park; Yoshitaka Shimizu; Kevin N O'Connor; Sunil Puria; Jin-Ho Cho
Journal:  Hear Res       Date:  2010-11-03       Impact factor: 3.208

6.  Fully implantable Otologics MET Carina device for the treatment of sensorineural hearing loss. Preliminary surgical and clinical results.

Authors:  L Bruschini; F Forli; A Santoro; P Bruschini; S Berrettini
Journal:  Acta Otorhinolaryngol Ital       Date:  2009-04       Impact factor: 2.124

7.  A Retrospective Multicentre Cohort Review of Patient Characteristics and Surgical Aspects versus the Long-Term Outcomes for Recipients of a Fully Implantable Active Middle Ear Implant.

Authors:  Philippe P Lefebvre; Javier Gisbert; Domenico Cuda; Stéphane Tringali; Arnaud Deveze
Journal:  Audiol Neurootol       Date:  2017-01-05       Impact factor: 1.854

8.  A Fully-Implantable Cochlear Implant SoC with Piezoelectric Middle-Ear Sensor and Arbitrary Waveform Neural Stimulation.

Authors:  Marcus Yip; Rui Jin; Hideko Heidi Nakajima; Konstantina M Stankovic; Anantha P Chandrakasan
Journal:  IEEE J Solid-State Circuits       Date:  2015-01-01       Impact factor: 5.013

Review 9.  Middle ear implantable hearing devices: an overview.

Authors:  David S Haynes; Jadrien A Young; George B Wanna; Michael E Glasscock
Journal:  Trends Amplif       Date:  2009-09

10.  The Carina© middle ear implant: surgical and functional outcomes.

Authors:  Luca Bruschini; Stefano Berrettini; Francesca Forli; Alessandra Murri; Domenico Cuda
Journal:  Eur Arch Otorhinolaryngol       Date:  2016-03-23       Impact factor: 2.503

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