Literature DB >> 17665462

Treatment of older adult patients diagnosed with rheumatoid arthritis: improved but not optimal.

Gabriela Schmajuk1, Sebastian Schneeweiss, Jeffrey N Katz, Michael E Weinblatt, Soko Setoguchi, Jerry Avorn, Raisa Levin, Daniel H Solomon.   

Abstract

OBJECTIVE: The National Committee on Quality Assurance has determined that all patients with rheumatoid arthritis (RA) should be treated with disease-modifying antirheumatic drugs (DMARDs). Our objective was to determine the rate and predictors of DMARD use in a cohort of elderly patients with RA.
METHODS: We analyzed health care utilization data for 5,864 Medicare beneficiaries with RA who also participated in a state-run pharmaceutical benefit program in Pennsylvania. Patients with RA were defined as those with at least 3 diagnoses of RA (International Classification of Diseases, Ninth Revision code 714.xx) at least 1 week apart who were enrolled in these programs for at least 12 months during 1995-2004. Multivariate logistic regression was used to assess predictors of synthetic or biologic DMARD use in the 12 months after cohort entry.
RESULTS: Thirty percent of patients filled a DMARD prescription during 12 months of followup. Frequency of DMARD use increased steadily over time: 24% received DMARDs in 1996 compared with 43% in 2003 (P for trend <0.001). Of patients with at least 1 rheumatologist visit, 41% received a DMARD in 1996 compared with 70% in 2003 (P < 0.001). After the introduction of biologic DMARDs in 1998, 6% of all patients with RA received a biologic, including 12% who saw a rheumatologist. Patients ages 75-84 were 52% less likely to receive DMARDs (95% confidence interval [95% CI] 46-58%) and patients ages >or=85 were 74% less likely (95% CI 69-79%) compared with patients ages 65-74.
CONCLUSION: In this cohort of patients in the community with full prescription drug coverage, most patients diagnosed with RA did not receive a DMARD during the 12 months after cohort entry. Older patients and those not seeing a rheumatologist were less likely to receive a DMARD and may provide a target for quality improvement interventions.

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Year:  2007        PMID: 17665462     DOI: 10.1002/art.22890

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  55 in total

1.  Role of community and individual characteristics in physician visits for persons with systemic lupus erythematosus.

Authors:  Chris Tonner; Laura Trupin; Jinoos Yazdany; Lindsey Criswell; Patricia Katz; Edward Yelin
Journal:  Arthritis Care Res (Hoboken)       Date:  2010-06       Impact factor: 4.794

2.  Factors that influence rheumatologists' decisions to escalate care in rheumatoid arthritis: results from a choice-based conjoint analysis.

Authors:  Wietske Kievit; Laura van Hulst; Piet van Riel; Liana Fraenkel
Journal:  Arthritis Care Res (Hoboken)       Date:  2010-06       Impact factor: 4.794

3.  An evaluation of the impact of seniors on a rheumatology referral clinic: demographics and pharmacotherapy.

Authors:  Angela Juby; Paul Davis
Journal:  Clin Rheumatol       Date:  2011-09-21       Impact factor: 2.980

4.  Changes in cotherapies after initiation of disease-modifying antirheumatic drug therapy in patients with rheumatoid arthritis.

Authors:  Vivian K Kawai; Carlos G Grijalva; Patrick G Arbogast; Jeffrey R Curtis; Daniel H Solomon; Elizabeth Delzell; Lang Chen; Rita Ouellet-Hellstrom; Lisa Herrinton; Liyan Liu; Edward F Mitchel; C Michael Stein; Marie R Griffin
Journal:  Arthritis Care Res (Hoboken)       Date:  2011-10       Impact factor: 4.794

5.  A Multistakeholder Approach to Improving Quality in Rheumatoid Arthritis: Proceedings from the Rheumatoid Arthritis Quality Expert Medical Panel.

Authors:  Jeffrey R Curtis; C Kent Kwoh; Albert J Rizzoli; John A Welz
Journal:  Am Health Drug Benefits       Date:  2014-11

6.  Receipt of disease-modifying antirheumatic drugs among patients with rheumatoid arthritis in Medicare managed care plans.

Authors:  Gabriela Schmajuk; Amal N Trivedi; Daniel H Solomon; Edward Yelin; Laura Trupin; Eliza F Chakravarty; Jinoos Yazdany
Journal:  JAMA       Date:  2011-02-02       Impact factor: 56.272

7.  Routinely measuring and reporting pneumococcal vaccination among immunosuppressed rheumatology outpatients: the first step in improving quality.

Authors:  Sonali P Desai; Alexander Turchin; Lara E Szent-Gyorgyi; Michael Weinblatt; Jonathan Coblyn; Daniel H Solomon; Allen Kachalia
Journal:  Rheumatology (Oxford)       Date:  2010-10-24       Impact factor: 7.580

8.  Use of disease-modifying medications for rheumatoid arthritis by race and ethnicity in the National Ambulatory Medical Care Survey.

Authors:  Daniel H Solomon; John Z Ayanian; Ed Yelin; Tamara Shaykevich; M Alan Brookhart; Jeffrey N Katz
Journal:  Arthritis Care Res (Hoboken)       Date:  2012-02       Impact factor: 4.794

Review 9.  Review: treat to target in rheumatoid arthritis: fact, fiction, or hypothesis?

Authors:  Daniel H Solomon; Asaf Bitton; Jeffrey N Katz; Helga Radner; Erika M Brown; Liana Fraenkel
Journal:  Arthritis Rheumatol       Date:  2014-04       Impact factor: 10.995

10.  Lipid testing in patients with rheumatoid arthritis and key cardiovascular-related comorbidities: a medicare analysis.

Authors:  Christie M Bartels; Amy J H Kind; Carolyn T Thorpe; Christine M Everett; Rachel J Cook; Patrick E McBride; Maureen A Smith
Journal:  Semin Arthritis Rheum       Date:  2012-03-16       Impact factor: 5.532

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