Literature DB >> 17658816

Stereocontrolled synthesis of dafachronic acid A, the ligand for the DAF-12 nuclear receptor of Caenorhabditis elegans.

Simon Giroux1, E J Corey.   

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Year:  2007        PMID： 17658816     DOI： 10.1021/ja074306i

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


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  9 in total

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2.  A photocleavable masked nuclear-receptor ligand enables temporal control of C. elegans development.

Authors:  Joshua C Judkins; Parag Mahanti; Jacob B Hoffman; Isaiah Yim; Adam Antebi; Frank C Schroeder
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Authors:  Yandong Zhang; Samuel J Danishefsky
Journal:  J Am Chem Soc       Date:  2010-07-21       Impact factor: 15.419

4.  Access to functionalized steroid side chains via modified Julia olefination.

Authors:  Enver Cagri Izgu; Aaron C Burns; Thomas R Hoye
Journal:  Org Lett       Date:  2011-01-18       Impact factor: 6.005

5.  Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.

Authors:  Zhu Wang; X Edward Zhou; Daniel L Motola; Xin Gao; Kelly Suino-Powell; Aoife Conneely; Craig Ogata; Kamalesh K Sharma; Richard J Auchus; James B Lok; John M Hawdon; Steven A Kliewer; H Eric Xu; David J Mangelsdorf
Journal:  Proc Natl Acad Sci U S A       Date:  2009-06-02       Impact factor: 11.205

6.  A conserved endocrine mechanism controls the formation of dauer and infective larvae in nematodes.

Authors:  Akira Ogawa; Adrian Streit; Adam Antebi; Ralf J Sommer
Journal:  Curr Biol       Date:  2008-12-24       Impact factor: 10.834

7.  Syntheses and biological evaluation of B-ring-modified analogues of dafachronic acid A.

Authors:  Simon Giroux; Axel Bethke; Nicole Fielenbach; Adam Antebi; E J Corey
Journal:  Org Lett       Date:  2008-07-19       Impact factor: 6.005

8.  Convenient method for the functionalization of the 4- and 6-positions of the androgen skeleton.

Authors:  Daniel Morton; Allison R Dick; Debashis Ghosh; Huw M L Davies
Journal:  Chem Commun (Camb)       Date:  2012-05-09       Impact factor: 6.222

9.  Synthesis and activity of dafachronic acid ligands for the C. elegans DAF-12 nuclear hormone receptor.

Authors:  Kamalesh K Sharma; Zhu Wang; Daniel L Motola; Carolyn L Cummins; David J Mangelsdorf; Richard J Auchus
Journal:  Mol Endocrinol       Date:  2009-02-05
  9 in total

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