Literature DB >> 17617698

Abyssomicins G and H and atrop-abyssomicin C from the marine Verrucosispora strain AB-18-032.

Simone Keller1, Graeme Nicholson, Carmen Drahl, Erik Sorensen, Hans-Peter Fiedler, Roderich D Süssmuth.   

Abstract

Abyssomicin C is a complex polyketide-type antibiotic and the first natural inhibitor of the p-aminobenzoate biosynthesis produced by the marine Verrucosispora strain AB-18-032. We have now isolated three novel naturally produced abyssomicins, among them the even more active atrop-abyssomicin C. The chemical structures were elucidated by mass spectrometry and NMR spectroscopy.

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Year:  2007        PMID: 17617698     DOI: 10.1038/ja.2007.54

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  29 in total

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Review 2.  Constructing molecular complexity and diversity: total synthesis of natural products of biological and medicinal importance.

Authors:  K C Nicolaou; Christopher R H Hale; Christian Nilewski; Heraklidia A Ioannidou
Journal:  Chem Soc Rev       Date:  2012-06-28       Impact factor: 54.564

3.  Molecular networking as a dereplication strategy.

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Journal:  J Nat Prod       Date:  2013-09-11       Impact factor: 4.050

Review 4.  Recent advances in the chemistry and biology of naturally occurring antibiotics.

Authors:  K C Nicolaou; Jason S Chen; David J Edmonds; Anthony A Estrada
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

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Authors:  Salim Javed; Mahipal Bodugam; Jessica Torres; Arghya Ganguly; Paul R Hanson
Journal:  Chemistry       Date:  2016-04-05       Impact factor: 5.236

6.  Genome sequence of the abyssomicin- and proximicin-producing marine actinomycete Verrucosispora maris AB-18-032.

Authors:  Hanseong Roh; Gabriel C Uguru; Hyeok-Jin Ko; Sujin Kim; Byung-Yong Kim; Michael Goodfellow; Alan T Bull; Kyoung Heon Kim; Mervyn J Bibb; In-Geol Choi; James E M Stach
Journal:  J Bacteriol       Date:  2011-05-06       Impact factor: 3.490

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Journal:  Org Lett       Date:  2015-01-05       Impact factor: 6.005

Review 8.  Natural [4 + 2]-Cyclases.

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Journal:  Chem Rev       Date:  2016-12-01       Impact factor: 60.622

Review 9.  A brief history of antibiotics and select advances in their synthesis.

Authors:  Kyriacos C Nicolaou; Stephan Rigol
Journal:  J Antibiot (Tokyo)       Date:  2017-07-05       Impact factor: 2.649

Review 10.  Novel anti-infective compounds from marine bacteria.

Authors:  Hafizur Rahman; Brian Austin; Wilfrid J Mitchell; Peter C Morris; Derek J Jamieson; David R Adams; Andrew Mearns Spragg; Michael Schweizer
Journal:  Mar Drugs       Date:  2010-03-05       Impact factor: 5.118

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