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Literature DB >> 17592850

Exploiting temperature-dependent substrate promiscuity for nucleoside analogue activation by thymidine kinase from Thermotoga maritima.

Stefan Lutz¹, Joseph Lichter, Lingfeng Liu.

Abstract

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 2007 PMID： 17592850 PMCID： PMC2085358 DOI： 10.1021/ja0734391

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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13 in total

1. REACTION OF PAPAIN WITH ETHYL (CARBONYL-18O)HIPPURATE.

Authors: J F KIRSCH; E KATCHALSKI
Journal: Biochemistry Date: 1965-05 Impact factor: 3.162

2. Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs.

Authors: S Eriksson; B Kierdaszuk; B Munch-Petersen; B Oberg; N G Johansson
Journal: Biochem Biophys Res Commun Date: 1991-04-30 Impact factor: 3.575

Review 3. Industrial relevance of thermophilic Archaea.

Authors: Ksenia Egorova; Garabed Antranikian
Journal: Curr Opin Microbiol Date: 2005-10-27 Impact factor: 7.934

4. Structures of thymidine kinase 1 of human and mycoplasmic origin.

Authors: Martin Welin; Urszula Kosinska; Nils-Egil Mikkelsen; Cecilia Carnrot; Chunying Zhu; Liya Wang; Staffan Eriksson; Birgitte Munch-Petersen; Hans Eklund
Journal: Proc Natl Acad Sci U S A Date: 2004-12-20 Impact factor: 11.205

5. Evidence for a rate-limiting conformation change in the catalytic steps of the ficin and papain-catalysed hydrolyses of benzyloxycarbonyl-L-lysine p-nitrophenyl ester.

Authors: M R Hollaway; M J Hardman
Journal: Eur J Biochem Date: 1973-02-01

6. Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure.

Authors: Dario Segura-Peña; Stefan Lutz; Christian Monnerjahn; Manfred Konrad; Arnon Lavie
Journal: J Mol Biol Date: 2007-03-15 Impact factor: 5.469

7. Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding.

Authors: Urszula Kosinska; Cecilia Carnrot; Michael P B Sandrini; Anders R Clausen; Liya Wang; Jure Piskur; Staffan Eriksson; Hans Eklund
Journal: FEBS J Date: 2007-02 Impact factor: 5.542

8. Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins.

Authors: P Závodszky; J Kardos; G A Petsko
Journal: Proc Natl Acad Sci U S A Date: 1998-06-23 Impact factor: 11.205

9. Structure of human dCK suggests strategies to improve anticancer and antiviral therapy.

Authors: Elisabetta Sabini; Stephan Ort; Christian Monnerjahn; Manfred Konrad; Arnon Lavie
Journal: Nat Struct Biol Date: 2003-07

10. Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker.

Authors: Victor E Marquez; Tsipi Ben-Kasus; Joseph J Barchi; Karen M Green; Marc C Nicklaus; Riad Agbaria
Journal: J Am Chem Soc Date: 2004-01-21 Impact factor: 16.383

6 in total

Exploiting temperature-dependent substrate promiscuity for nucleoside analogue activation by thymidine kinase from Thermotoga maritima.

1. REACTION OF PAPAIN WITH ETHYL (CARBONYL-18O)HIPPURATE.

2. Comparison of the substrate specificities of human thymidine kinase 1 and 2 and deoxycytidine kinase toward antiviral and cytostatic nucleoside analogs.

Review 3. Industrial relevance of thermophilic Archaea.

4. Structures of thymidine kinase 1 of human and mycoplasmic origin.

5. Evidence for a rate-limiting conformation change in the catalytic steps of the ficin and papain-catalysed hydrolyses of benzyloxycarbonyl-L-lysine p-nitrophenyl ester.

6. Binding of ATP to TK1-like enzymes is associated with a conformational change in the quaternary structure.

7. Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding.

8. Adjustment of conformational flexibility is a key event in the thermal adaptation of proteins.

9. Structure of human dCK suggests strategies to improve anticancer and antiviral therapy.

10. Experimental and structural evidence that herpes 1 kinase and cellular DNA polymerase(s) discriminate on the basis of sugar pucker.

1. Quaternary structure change as a mechanism for the regulation of thymidine kinase 1-like enzymes.

Review 2. Protein promiscuity and its implications for biotechnology.

3. Engineering Kinases to Phosphorylate Nucleoside Analogs for Antiviral and Cancer Therapy.

4. Engineering substrate promiscuity in 2,4-dichlorophenol hydroxylase by in silico design.

5. Quantitative Detection of Nucleoside Analogues by Multi-enzyme Biosensors using Time-Resolved Kinetic Measurements.

6. Inactive-to-Active Transition of Human Thymidine Kinase 1 Revealed by Molecular Dynamics Simulations.