BACKGROUND: Although ocular tonography measures a pulsatile component of the ocular perfusion, the retinal and/or choroidal components of this pulsatile flow remain undefined. AIM: To compare ocular tonography with the assessment of flow velocities in arteries supplying the retina, choroid and entire orbit. METHODS: 22 normal eyes from 11 subjects were studied. Pulsatile ocular blood flow (POBF) was measured using the ocular blood flow tonograph, and flow velocities in the ophthalmic, central retinal (CRA) and temporal short posterior ciliary arteries (TSPCA) using colour Doppler imaging. The correlation between POBF and retrobulbar flow velocities was determined. RESULTS: POBF correlated significantly with peak systolic velocity (PSV) of the CRA (r = 0.56, p = 0.007) and the TSPCA (r = 0.48, p = 0.02), and with the resistive index of the TSPCA (r = 0.45, p = 0.04). Additionally, pulse amplitude (PSV-end diastolic velocity) in the CRA and the TSPCA correlated significantly with POBF measurements (each p<0.05). However, POBF did not correlate with any flow velocity indices in the ophthalmic artery. CONCLUSION: POBF is associated with systolic and pulsatile components of blood flow velocities in both the CRA and the TSPCA. This result suggests that POBF determinations are influenced by the pulsatile components of both choroidal and retinal perfusion.
BACKGROUND: Although ocular tonography measures a pulsatile component of the ocular perfusion, the retinal and/or choroidal components of this pulsatile flow remain undefined. AIM: To compare ocular tonography with the assessment of flow velocities in arteries supplying the retina, choroid and entire orbit. METHODS: 22 normal eyes from 11 subjects were studied. Pulsatile ocular blood flow (POBF) was measured using the ocular blood flow tonograph, and flow velocities in the ophthalmic, central retinal (CRA) and temporal short posterior ciliary arteries (TSPCA) using colour Doppler imaging. The correlation between POBF and retrobulbar flow velocities was determined. RESULTS: POBF correlated significantly with peak systolic velocity (PSV) of the CRA (r = 0.56, p = 0.007) and the TSPCA (r = 0.48, p = 0.02), and with the resistive index of the TSPCA (r = 0.45, p = 0.04). Additionally, pulse amplitude (PSV-end diastolic velocity) in the CRA and the TSPCA correlated significantly with POBF measurements (each p<0.05). However, POBF did not correlate with any flow velocity indices in the ophthalmic artery. CONCLUSION: POBF is associated with systolic and pulsatile components of blood flow velocities in both the CRA and the TSPCA. This result suggests that POBF determinations are influenced by the pulsatile components of both choroidal and retinal perfusion.
Authors: P Gunvant; M Baskaran; L Vijaya; B C Hansen; I S Joseph; R J Watkins; D C Broadway; D J O'Leary Journal: Eye (Lond) Date: 2005-11 Impact factor: 3.775
Authors: P Gunvant; M Baskaran; L Vijaya; I S Joseph; R J Watkins; M Nallapothula; D C Broadway; D J O'Leary Journal: Br J Ophthalmol Date: 2004-04 Impact factor: 4.638
Authors: Alexandra Benavente-Pérez; Sarah L Hosking; Nicola S Logan; David C Broadway Journal: Graefes Arch Clin Exp Ophthalmol Date: 2010-05-26 Impact factor: 3.117
Authors: Jan Studnička; Eva Rencová; Milan Bláha; Pavel Rozsíval; Miriam Lánská; Vladimír Bláha; Jan Němčanský; Hana Langrová Journal: J Ophthalmol Date: 2013-12-18 Impact factor: 1.909
Authors: Magdalena Asejczyk-Widlicka; Patrycja Krzyzanowska-Berkowska; Beata P Sander; D Robert Iskander Journal: PLoS One Date: 2015-07-28 Impact factor: 3.240