| Literature DB >> 17546658 |
Nien-Yeen Hsu1, Wen-Bin Yang, Chi-Huey Wong, Yuan-Chuan Lee, Reiko T Lee, Yi-Sheng Wang, Chung-Hsuan Chen.
Abstract
So far, there have been only a few matrices reported for detection of polysaccharides with molecular weight higher than 3000 Daltons by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). In this work, we found that 2',4',6'-trihydroxyacetophenone (THAP) is a good matrix for MALDI time-of-flight MS analysis of polysaccharides with broad mass range. Large polysaccharides, dextrans, glycoproteins and polysialic acids have been successfully detected by MALDI-MS with THAP as matrix. Copyright (c) 2007 John Wiley & Sons, Ltd.Entities:
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Year: 2007 PMID: 17546658 DOI: 10.1002/rcm.3072
Source DB: PubMed Journal: Rapid Commun Mass Spectrom ISSN: 0951-4198 Impact factor: 2.419