Literature DB >> 17534463

Antihypertensive medication use by recently diagnosed hypertensive Canadians.

C Ineke Neutel1, Norm R C Campbell.   

Abstract

PURPOSE: The Canadian Hypertension Education Program (CHEP) was initiated in 1999 to improve hypertension management in Canada. The objective of the present study was to compare antihypertensive pharmacotherapy in Canada before and after the CHEP.
METHODS: Data were obtained from the longitudinal National Population Health Surveys, which consisted of five cycles at two-year intervals from 1994 to 2002. Recent hypertensive respondents 20 years of age and older were identified the first time hypertension was reported or treated, and were included in a study population of 1453 newly diagnosed hypertensive patients. Persistence with medication use was assessed in the cycle after the first report of hypertension.
RESULTS: Antihypertensive medication use within two years of hypertension diagnosis increased with age, from 35% in patients 20 to 39 years of age, to 72.1% in those 80 years of age and older. Antihypertensive medication use increased after the CHEP (from 49.2% to 53.8% of the population), as did the use of multiple antihypertensive medications (from 7.5% to 10.6%). The most commonly used antihypertensive medication for men was angiotensin-converting enzyme inhibitors (beta-blockers were second), but the most common medication for women was diuretics. The overall persistence rate for antihypertensive medication use was 73.2% over two years, which had increased after the CHEP (from 70.4% to 75.4%).
CONCLUSIONS: The implementation of the CHEP was followed by increased antihypertensive medication use, increased use of multiple antihypertensive medications and improved persistence with medication use. Although causality cannot be established with the design of the present study, improved hypertension management in Canada is heartening. Sex-related differences were observed in prescribed medications, even though clinical guidelines do not differentiate between sexes.

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Year:  2007        PMID: 17534463      PMCID: PMC2650760          DOI: 10.1016/s0828-282x(07)70801-2

Source DB:  PubMed          Journal:  Can J Cardiol        ISSN: 0828-282X            Impact factor:   5.223


  24 in total

1.  The Canadian Hypertension Education Program (CHEP) recommendations: launching a new series.

Authors:  Finlay A McAlister; Eric Wooltorton; Norman R C Campbell
Journal:  CMAJ       Date:  2005-08-30       Impact factor: 8.262

Review 2.  Adherence to medication.

Authors:  Lars Osterberg; Terrence Blaschke
Journal:  N Engl J Med       Date:  2005-08-04       Impact factor: 91.245

3.  Changes in cardiovascular deaths and hospitalization in Canada.

Authors:  Norm R C Campbell; Jay Onysko; Helen Johansen; Ru-Nie Gao
Journal:  Can J Cardiol       Date:  2006-04       Impact factor: 5.223

4.  Differential persistence with initial antihypertensive therapies: a clue for understanding the needs of hypertensive patients.

Authors:  Bernard Waeber; Michel Burnier
Journal:  J Hypertens       Date:  2006-06       Impact factor: 4.844

5.  The impact of the Canadian Hypertension Education Program on antihypertensive prescribing trends.

Authors:  Norman R C Campbell; Karen Tu; Rollin Brant; Minh Duong-Hua; Finlay A McAlister
Journal:  Hypertension       Date:  2005-12-12       Impact factor: 10.190

6.  Effect of initial drug choice on persistence with antihypertensive therapy: the importance of actual practice data.

Authors:  J J Caro; J L Speckman; M Salas; G Raggio; J D Jackson
Journal:  CMAJ       Date:  1999-01-12       Impact factor: 8.262

7.  Variations in compliance among hypertensive patients by drug class: implications for health care costs.

Authors:  J A Rizzo; W R Simons
Journal:  Clin Ther       Date:  1997 Nov-Dec       Impact factor: 3.393

8.  Hypertension management in the elderly has improved: Ontario prescribing trends, 1994 to 2002.

Authors:  Karen Tu; Norman R C Campbell; Minh Duong-Hua; Finlay A McAlister
Journal:  Hypertension       Date:  2005-04-25       Impact factor: 10.190

9.  Awareness and misconception of hypertension in Canada: results of a national survey.

Authors:  Robert J Petrella; N R C Campbell
Journal:  Can J Cardiol       Date:  2005-05-15       Impact factor: 5.223

10.  MRC trial of treatment of mild hypertension: principal results. Medical Research Council Working Party.

Authors: 
Journal:  Br Med J (Clin Res Ed)       Date:  1985-07-13
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  11 in total

1.  Management of hypertension: Regional variations in a greatly improved landscape.

Authors:  Sheldon W Tobe
Journal:  Can J Cardiol       Date:  2010-10       Impact factor: 5.223

2.  Blood Pressure Control in Canada: Through the Looking-Glass Into a Glass Half Empty?

Authors:  Raj Padwal; Norm R C Campbell
Journal:  Am J Hypertens       Date:  2017-03-01       Impact factor: 2.689

3.  The risk of falls on initiation of antihypertensive drugs in the elderly.

Authors:  D A Butt; M Mamdani; P C Austin; K Tu; T Gomes; R H Glazier
Journal:  Osteoporos Int       Date:  2013-04-24       Impact factor: 4.507

4.  Characteristics Associated With Antihypertensive Treatment and Blood Pressure Control: A Population-Based Follow-Up Study in Peru.

Authors:  J Alfredo Zavala-Loayza; Catherine Pastorius Benziger; María Kathia Cárdenas; Rodrigo M Carrillo-Larco; Antonio Bernabé-Ortiz; Robert H Gilman; William Checkley; J Jaime Miranda
Journal:  Glob Heart       Date:  2016-03

Review 5.  Canadian Hypertension Education Program: the evolution of hypertension management guidelines in Canada.

Authors:  Ross D Feldman; Norman R C Campbell; Katherine Wyard
Journal:  Can J Cardiol       Date:  2008-06       Impact factor: 5.223

6.  Characteristics of hypertensive Canadians not receiving drug therapy.

Authors:  Norman R C Campbell; Lawrence So; Ernest Amankwah; Hude Quan; Colleen Maxwell
Journal:  Can J Cardiol       Date:  2008-06       Impact factor: 5.223

Review 7.  The 2008 Canadian Hypertension Education Program recommendations: the scientific summary -- an annual update.

Authors: 
Journal:  Can J Cardiol       Date:  2008-06       Impact factor: 5.223

8.  2006 Ontario Survey on the Prevalence and Control of Hypertension (ON-BP): rationale and design of a community-based cross-sectional survey.

Authors:  J George Fodor; Frans H H Leenen; Eftyhia Helis; Penelope Turton
Journal:  Can J Cardiol       Date:  2008-06       Impact factor: 5.223

9.  Comparison of the Effect of Thiazide Diuretics and Other Antihypertensive Drugs on Central Blood Pressure: Cross-Sectional Analysis Among Nondiabetic Patients.

Authors:  Cristiano S Moura; Stella S Daskalopoulou; Linda E Levesque; Sasha Bernatsky; Michal Abrahamowicz; Meytal A Tsadok; Shadi Rajabi; Louise Pilote
Journal:  J Clin Hypertens (Greenwich)       Date:  2015-07-20       Impact factor: 3.738

10.  Do recommendations for the management of hypertension improve cardiovascular outcome? The canadian experience.

Authors:  Peter Bolli; Norm R C Campbell
Journal:  Int J Hypertens       Date:  2011-10-30       Impact factor: 2.420

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