Literature DB >> 15851629

Hypertension management in the elderly has improved: Ontario prescribing trends, 1994 to 2002.

Karen Tu1, Norman R C Campbell, Minh Duong-Hua, Finlay A McAlister.   

Abstract

To examine whether the treatment of elderly hypertensives had become more aggressive over the past decade, we evaluated: (1) the frequency of new prescriptions for hypertension treatment, adjusted by age and gender; (2) the frequency with which multiple antihypertensives were prescribed concurrently within 2 years of initial diagnosis; and (3) discontinuation rates for antihypertensive therapy. We linked 4 administrative databases and a province-wide clinical database in Ontario, Canada, to derive a cohort of patients > or =66 years of age who were newly started on an antihypertensive agent between July 1, 1994, and March 31, 2002, without another indication for the agent (all patients were followed for 2 years after their initial antihypertensive prescription). Our cohort consisted of 196 451 people newly started on antihypertensive therapy, 30 433 of whom also had diabetes mellitus. The population-adjusted rate of new antihypertensive prescriptions increased by 30% between 1994 and 2002. Whereas 21% of patients newly diagnosed with hypertension in 1994 were prescribed multiple antihypertensives concurrently within 2 years of diagnosis, this proportion had increased to 40% by 2002 (P<0.0001). In the cohort of patients first prescribed an antihypertensive in 1994, 36% were not taking any antihypertensive within 2 years; only 21% of patients first prescribed an antihypertensive in 2002 had discontinued all therapy within 2 years (P<0.0001). Our data provide evidence that the physician management of hypertension in elderly Canadians became more aggressive between 1994 and 2002.

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Year:  2005        PMID: 15851629     DOI: 10.1161/01.HYP.0000164573.01177.95

Source DB:  PubMed          Journal:  Hypertension        ISSN: 0194-911X            Impact factor:   10.190


  23 in total

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Review 5.  Identification of factors driving differences in cost effectiveness of first-line pharmacological therapy for uncomplicated hypertension.

Authors:  Scott W Klarenbach; Finlay A McAlister; Helen Johansen; Karen Tu; Maureen Hazel; Robin Walker; Kelly B Zarnke; Norman R C Campbell
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6.  Changes in the rates of awareness, treatment and control of hypertension in Canada over the past two decades.

Authors:  Finlay A McAlister; Kathryn Wilkins; Michel Joffres; Frans H H Leenen; George Fodor; Marianne Gee; Mark S Tremblay; Robin Walker; Helen Johansen; Norm Campbell
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7.  Trends in the incidence and outcomes of heart failure in Ontario, Canada: 1997 to 2007.

Authors:  Darwin F Yeung; Nicole K Boom; Helen Guo; Douglas S Lee; Susan E Schultz; Jack V Tu
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8.  From pharmaco-therapy to pharmaco-prevention: trends in prescribing to older adults in Ontario, Canada, 1997-2006.

Authors:  Jana M Bajcar; Li Wang; Rahim Moineddin; Jason X Nie; C Shawn Tracy; Ross Eg Upshur
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9.  Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in Canada.

Authors:  Michel R Joffres; Norm R C Campbell; Braden Manns; Karen Tu
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10.  Laboratory testing in newly treated elderly hypertensive patients without co-morbidities: a population-based cohort study.

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Journal:  Open Med       Date:  2007-06-12
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