Literature DB >> 17534391

Surgery insight: radical vaginal trachelectomy as a method of fertility preservation for cervical cancer.

Mario E Beiner1, Allan Covens.   

Abstract

Over the past decade, the treatment of cervical cancer has evolved with an increased emphasis on preservation of fertility. There has been a gradual abandonment of radical surgical procedures in favor of more conservative techniques in an effort to decrease morbidity and preserve fertility without compromising overall survival. Radical vaginal trachelectomy (RVT) with laparoscopic pelvic lymphadenectomy is a fertility-preserving procedure that has recently gained worldwide acceptance as a method of surgically treating small invasive cancers of the cervix. Since the original description of RVT by Daniel Dargent in 1994, over 500 cases of utilization of this technique have been reported in the literature, with over 100 live births reported following this procedure. The morbidity associated with RVT is low, with a tumor recurrence rate of 5% and a mortality rate of 3%. The current literature indicates no difference in the rate of recurrence with this technique compared with radical hysterectomy when proper selection criteria are used. Combining RVT with laparoscopic sentinel lymph-node biopsy can further reduce the duration, extent, and complications of surgery.

Entities:  

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Year:  2007        PMID: 17534391     DOI: 10.1038/ncponc0822

Source DB:  PubMed          Journal:  Nat Clin Pract Oncol        ISSN: 1743-4254


  20 in total

1.  Surgical management of early cervical cancer: the shape of future studies.

Authors:  Stefano Greggi; Cono Scaffa
Journal:  Curr Oncol Rep       Date:  2012-12       Impact factor: 5.075

2.  Conservative surgery in early-stage cervical cancer: what percentage of patients may be eligible for conization and lymphadenectomy?

Authors:  Ashlee L Smith; Michael Frumovitz; Kathleen M Schmeler; Ricardo dos Reis; Alpa M Nick; Robert L Coleman; Pedro T Ramirez
Journal:  Gynecol Oncol       Date:  2010-08-12       Impact factor: 5.482

3.  Expanding the indications for radical trachelectomy: a report on 29 patients with stage IB1 tumors measuring 2 to 4 centimeters.

Authors:  Stephanie L Wethington; Yukio Sonoda; Kay J Park; Kaled M Alektiar; William P Tew; Dennis S Chi; Mario M Leitao; Elizabeth L Jewell; Richard R Barakat; Nadeem R Abu-Rustum
Journal:  Int J Gynecol Cancer       Date:  2013-07       Impact factor: 3.437

Review 4.  Fertility-Sparing Options in Young Women with Cervical Cancer.

Authors:  Federica Tomao; Giacomo Corrado; Fedro Alessandro Peccatori; Sara Boveri; Eleonora Petra Preti; Nicoletta Colombo; Fabio Landoni
Journal:  Curr Treat Options Oncol       Date:  2016-01

5.  Conservatively treated glassy cell carcinoma of the cervix.

Authors:  Gabriella Ferrandina; Vanda Salutari; Marco Petrillo; Arnaldo Carbone; Giovanni Scambia
Journal:  World J Surg Oncol       Date:  2008-08-28       Impact factor: 2.754

6.  Stage IB1 cervical cancer: role of preoperative MR imaging in selection of patients for fertility-sparing radical trachelectomy.

Authors:  Yulia Lakhman; Oguz Akin; Kay J Park; Debra M Sarasohn; Junting Zheng; Debra A Goldman; Michael J Sohn; Chaya S Moskowitz; Yukio Sonoda; Hedvig Hricak; Nadeem R Abu-Rustum
Journal:  Radiology       Date:  2013-06-20       Impact factor: 11.105

7.  Conservative treatment in early cervical cancer.

Authors:  Mojgan Karimi-Zarchi; Azamsadat Mousavi; Mitra Modares Gilani; Esmat Barooti; Ashrafosadat Miratashi-Yazdi; Atefe Dehghani
Journal:  Int J Biomed Sci       Date:  2013-09

8.  Fertility-preserving surgery in patients with early stage cervical carcinoma.

Authors:  Spyridon Kardakis
Journal:  ISRN Oncol       Date:  2012-12-18

9.  Fertility-sparing surgery for early-stage cervical cancer.

Authors:  Adelaide Fernanda Ribeiro Cubal; Joana Isabel Ferreira Carvalho; Maria Fernanda Martins Costa; Ana Paula Tavares Branco
Journal:  Int J Surg Oncol       Date:  2012-07-08

Review 10.  Radical trachelectomy: the first step of fertility preservation in young women with cervical cancer (Review).

Authors:  Salvatore Gizzo; Emanuele Ancona; Carlo Saccardi; Tito Silvio Patrelli; Roberto Berretta; Omar Anis; Marco Noventa; Anna Bertocco; Simone Fagherazzi; Michela Longone; Lucia Vendemiati; Donato D'Antona; Giovanni Battista Nardelli
Journal:  Oncol Rep       Date:  2013-09-19       Impact factor: 3.906

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