PURPOSE: The purpose of the study was to provide reference data for computer-aided joint space analysis based on a semi-automated and computer-aided diagnostic system for the measurement of metacarpal-phalangeal and proximal-interphalangeal finger joint widths; additionally, the determination of sex differences and the investigation of changes in joint width with age were evaluated. PATIENTS AND METHODS: Eighty hundred and sixty-nine patients (351 female and 518 male) received radiographs of the hand for trauma and were screened for a host of conditions known to affect the joint spaces. All participants underwent measurements of joint space distances at the metacarpal-phalangeal articulation (JSD-MCP) from the thumb to the small finger and at the proximal-interphalangeal articulation (JSD-PIP) from the index finger to the small finger using computer-aided diagnosis technology with semi-automated edge detection. RESULTS: The study revealed an annual narrowing of the JSD of 0.6% for the JSD-MCP and for the JSD-PIP. Furthermore, the data demonstrated a notable age-related decrease in JSD, including an accentuated age-related joint space narrowing in women for both articulations. Additionally, males showed a significantly wider JSD-MCP (+11.1%) and JSD-PIP (+15.4%) compared with the female cohort in all age groups. CONCLUSION: Our data presented gender-specific and age-related normative reference values for computer-aided joint space analysis of the JSD-MCP and JSD-PIP that could be used to identify disease-related joint space narrowing, particularly in patients with osteoarthritis and rheumatoid arthritis commonly involving the peripheral small hand joints.
PURPOSE: The purpose of the study was to provide reference data for computer-aided joint space analysis based on a semi-automated and computer-aided diagnostic system for the measurement of metacarpal-phalangeal and proximal-interphalangeal finger joint widths; additionally, the determination of sex differences and the investigation of changes in joint width with age were evaluated. PATIENTS AND METHODS: Eighty hundred and sixty-nine patients (351 female and 518 male) received radiographs of the hand for trauma and were screened for a host of conditions known to affect the joint spaces. All participants underwent measurements of joint space distances at the metacarpal-phalangeal articulation (JSD-MCP) from the thumb to the small finger and at the proximal-interphalangeal articulation (JSD-PIP) from the index finger to the small finger using computer-aided diagnosis technology with semi-automated edge detection. RESULTS: The study revealed an annual narrowing of the JSD of 0.6% for the JSD-MCP and for the JSD-PIP. Furthermore, the data demonstrated a notable age-related decrease in JSD, including an accentuated age-related joint space narrowing in women for both articulations. Additionally, males showed a significantly wider JSD-MCP (+11.1%) and JSD-PIP (+15.4%) compared with the female cohort in all age groups. CONCLUSION: Our data presented gender-specific and age-related normative reference values for computer-aided joint space analysis of the JSD-MCP and JSD-PIP that could be used to identify disease-related joint space narrowing, particularly in patients with osteoarthritis and rheumatoid arthritis commonly involving the peripheral small hand joints.
Authors: J Böttcher; A Pfeil; A Rosholm; A Petrovitch; B E Seidl; A Malich; M L Schäfer; A Kramer; H J Mentzel; G Lehmann; G Hein; W A Kaiser Journal: Arthritis Rheum Date: 2005-12
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Authors: Alexander Pfeil; Julia Sommerfeld; Rosemarie Fröber; Gabriele Lehmann; Ansgar Malich; Andreas Hansch; Gunter Wolf; Joachim Böttcher Journal: Rheumatol Int Date: 2010-04-17 Impact factor: 2.631
Authors: Olga Schenk; Yinghe Huo; Koen L Vincken; Mart A van de Laar; Ina H H Kuper; Kees C H Slump; Floris P J G Lafeber; Hein J Bernelot Moens Journal: J Med Imaging (Bellingham) Date: 2016-11-23
Authors: Alexander Pfeil; Andreas Hansch; Gabriele Lehmann; Thorsten Eidner; Max L Schäfer; Peter Oelzner; Diane M Renz; Gunter Wolf; Gert Hein; Werner A Kaiser; Joachim Böttcher Journal: Rheumatol Int Date: 2008-10-25 Impact factor: 2.631
Authors: Kasper Huétink; Ronald van 't Klooster; Bart L Kaptein; Iain Watt; Margreet Kloppenburg; Rob G H H Nelissen; Johan H C Reiber; Berend C Stoel Journal: Skeletal Radiol Date: 2011-02-11 Impact factor: 2.199
Authors: Alexander Pfeil; Peter Oelzner; Klaus Bornholdt; Andreas Hansch; Gabriele Lehmann; Diane M Renz; Gunter Wolf; Joachim Böttcher Journal: Arthritis Res Ther Date: 2013-02-13 Impact factor: 5.156