OBJECTIVES: To evaluate the rate of progression of radiological joint space narrowing (JSN) in patients operated on for hip osteoarthritis (OA) and to determine its predictive factors. STUDY DESIGN: retrospective longitudinal trial of 61 patients who underwent total hip arthroplasty (THA) for hip OA (69 operated hips). Mean follow-up 81.2 +/- 9.9 months. Collected data: (1) standing frontal radiographs of the pelvis from diagnosis to surgery (246 films) for morphological evaluation and quantitative measurement of joint space width (JSW) (computerized reading of digitized X-rays); (2) demographic data (sex, age, body mass index, smoking status, professional and sporting activities, family history of OA); (3) clinical data (age at onset-diagnosis and THA, drug consumption, time from diagnosis to permanent disability, OA at other joints, previous THA of the contralateral hip). STATISTICS: multivariate analysis. RESULTS: The yearly mean narrowing (YMN) of MeanJSW was 0.43 +/- 0.43 mm/yr (median 0.29, range 0.03-2.55). YMN correlated inversely with joint space width at operation and follow-up duration, and was increased in atrophic OA (r = 0.71). The time between diagnosis and THA correlated with JSW at diagnosis, and was inversely correlated with age at onset and YMN. It was longer in patients with hypertrophic OA (r = 0.69). CONCLUSION: Rapid progression of JSN, older age and absence of osteophytes appear to be the main factors leading to THA.
OBJECTIVES: To evaluate the rate of progression of radiological joint space narrowing (JSN) in patients operated on for hip osteoarthritis (OA) and to determine its predictive factors. STUDY DESIGN: retrospective longitudinal trial of 61 patients who underwent total hip arthroplasty (THA) for hip OA (69 operated hips). Mean follow-up 81.2 +/- 9.9 months. Collected data: (1) standing frontal radiographs of the pelvis from diagnosis to surgery (246 films) for morphological evaluation and quantitative measurement of joint space width (JSW) (computerized reading of digitized X-rays); (2) demographic data (sex, age, body mass index, smoking status, professional and sporting activities, family history of OA); (3) clinical data (age at onset-diagnosis and THA, drug consumption, time from diagnosis to permanent disability, OA at other joints, previous THA of the contralateral hip). STATISTICS: multivariate analysis. RESULTS: The yearly mean narrowing (YMN) of MeanJSW was 0.43 +/- 0.43 mm/yr (median 0.29, range 0.03-2.55). YMN correlated inversely with joint space width at operation and follow-up duration, and was increased in atrophic OA (r = 0.71). The time between diagnosis and THA correlated with JSW at diagnosis, and was inversely correlated with age at onset and YMN. It was longer in patients with hypertrophic OA (r = 0.69). CONCLUSION: Rapid progression of JSN, older age and absence of osteophytes appear to be the main factors leading to THA.
Authors: Alexander Pfeil; Joachim Böttcher; Max L Schäfer; Bettina E Seidl; Mirco Schmidt; Alexander Petrovitch; Jens-Peter Heyne; Gabriele Lehmann; Peter Oelzner; Gert Hein; Gunter Wolf; Werner A Kaiser Journal: J Digit Imaging Date: 2007-03-24 Impact factor: 4.056
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Authors: D Chu Miow Lin; W M Reichmann; L Gossec; E Losina; P G Conaghan; J F Maillefert Journal: Osteoarthritis Cartilage Date: 2011-03-23 Impact factor: 6.576
Authors: Martha C Castaño Betancourt; Frederic Cailotto; Hanneke J Kerkhof; Frederique M F Cornelis; Sally A Doherty; Deborah J Hart; Albert Hofman; Frank P Luyten; Rose A Maciewicz; Massimo Mangino; Sarah Metrustry; Kenneth Muir; Marjolein J Peters; Fernando Rivadeneira; Maggie Wheeler; Weiya Zhang; Nigel Arden; Tim D Spector; Andre G Uitterlinden; Michael Doherty; Rik J U Lories; Ana M Valdes; Joyce B J van Meurs Journal: Proc Natl Acad Sci U S A Date: 2012-05-07 Impact factor: 11.205
Authors: Alexander Pfeil; Joachim Böttcher; Bettina E Seidl; Jens-Peter Heyne; Alexander Petrovitch; Torsten Eidner; Hans-Joachim Mentzel; Gunter Wolf; Gert Hein; Werner A Kaiser Journal: Skeletal Radiol Date: 2007-05-17 Impact factor: 2.199