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Literature DB >> 17502369

The interferons: 50 years after their discovery, there is much more to learn.

Abstract

The interferons (IFNs) and their receptors represent a subset of the class 2 alpha-helical cytokines that have been in chordates for millions of years. This brief review focuses on the discovery and purification of interferons, cloning of human IFN-alpha and IFN-beta, interferon receptors, activities and therapeutic uses of interferons, and the side effects of interferons.

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Year: 2007 PMID： 17502369 DOI： 10.1074/jbc.R700004200

Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157

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Cited

129 in total

Review 1. Induction and evasion of innate antiviral responses by hepatitis C virus.

Authors: Stanley M Lemon
Journal: J Biol Chem Date: 2010-05-10 Impact factor: 5.157

Review 2. The interferon signaling network and transcription factor C/EBP-beta.

Authors: Hui Li; Padmaja Gade; Weihua Xiao; Dhan V Kalvakolanu
Journal: Cell Mol Immunol Date: 2007-12 Impact factor: 11.530

3. Inducible deposition of the histone variant H3.3 in interferon-stimulated genes.

Authors: Tomohiko Tamura; Matthew Smith; Tomohiko Kanno; Hormuzdiyer Dasenbrock; Akira Nishiyama; Keiko Ozato
Journal: J Biol Chem Date: 2009-02-25 Impact factor: 5.157

4. Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursors.

Authors: Swarna Mehrotra; Bhumika Sharma; Sonali Joshi; Barbara Kroczynska; Beata Majchrzak; Brady L Stein; Brandon McMahon; Jessica K Altman; Jonathan D Licht; Darren P Baker; Elizabeth A Eklund; Amittha Wickrema; Amit Verma; Eleanor N Fish; Leonidas C Platanias
Journal: J Biol Chem Date: 2013-06-28 Impact factor: 5.157

5. Reduction of infection by inhibiting mTOR pathway is associated with reversed repression of type I interferon by porcine reproductive and respiratory syndrome virus.

Authors: Qinfang Liu; Laura C Miller; Frank Blecha; Yongming Sang
Journal: J Gen Virol Date: 2017-06-14 Impact factor: 3.891

6. Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase.

Authors: Laure Campillo-Gimenez; Mireille Laforge; Michèle Fay; Audrey Brussel; Marie-Christine Cumont; Valérie Monceaux; Ousmane Diop; Yves Lévy; Bruno Hurtrel; John Zaunders; Jacques Corbeil; Carole Elbim; Jérôme Estaquier
Journal: J Virol Date: 2009-11-25 Impact factor: 5.103

The interferons: 50 years after their discovery, there is much more to learn.

Review 1. Induction and evasion of innate antiviral responses by hepatitis C virus.

Review 2. The interferon signaling network and transcription factor C/EBP-beta.

3. Inducible deposition of the histone variant H3.3 in interferon-stimulated genes.

4. Essential role for the Mnk pathway in the inhibitory effects of type I interferons on myeloproliferative neoplasm (MPN) precursors.

5. Reduction of infection by inhibiting mTOR pathway is associated with reversed repression of type I interferon by porcine reproductive and respiratory syndrome virus.

6. Nonpathogenesis of simian immunodeficiency virus infection is associated with reduced inflammation and recruitment of plasmacytoid dendritic cells to lymph nodes, not to lack of an interferon type I response, during the acute phase.

7. Interferon-stimulated gene 15 as a general marker for acute and chronic neuronal injuries.

Review 8. Interferon-stimulated genes: a complex web of host defenses.

Review 9. Regulation of interferon-dependent mRNA translation of target genes.

10. Nuclear transit of the intracellular domain of the interferon receptor subunit IFNaR2 requires Stat2 and Irf9.