Literature DB >> 24559173

Regulation of interferon-dependent mRNA translation of target genes.

Barbara Kroczynska1, Swarna Mehrotra, Ahmet Dirim Arslan, Surinder Kaur, Leonidas C Platanias.   

Abstract

Interferons (IFNs) are released by cells on exposure to various stimuli, including viruses, double-stranded RNA, and other cytokines and various polypeptides. These IFNs play important physiological and pathophysiological roles in humans. Many clinical studies have established activity for these cytokines in the treatment of several malignancies, viral syndromes, and autoimmune disorders. In this review, the regulatory effects of type I and II IFN receptors on the translation-initiation process mediated by mechanistic target of rapamycin (mTOR) and mitogen-activated protein kinase (MAPK) pathways and the known mechanisms of control of mRNA translation of IFN-stimulated genes are summarized and discussed.

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Year:  2014        PMID： 24559173      PMCID： PMC3976582          DOI： 10.1089/jir.2013.0148

Source DB:  PubMed          Journal:  J Interferon Cytokine Res        ISSN： 1079-9907            Impact factor:   2.607


  97 in total

Review 1.  Full house: 12 receptors for 27 cytokines.

Authors:  Sergei V Kotenko; Jerome A Langer
Journal:  Int Immunopharmacol       Date:  2004-05       Impact factor: 4.932

2.  The protein kinase Akt1 regulates the interferon response through phosphorylation of the transcriptional repressor EMSY.

Authors:  Scott A Ezell; Christos Polytarchou; Maria Hatziapostolou; Ailan Guo; Ioannis Sanidas; Teeru Bihani; Michael J Comb; George Sourvinos; Philip N Tsichlis
Journal:  Proc Natl Acad Sci U S A       Date:  2012-02-06       Impact factor: 11.205

Review 3.  Mechanisms of mRNA translation of interferon stimulated genes.

Authors:  Sonali Joshi; Surinder Kaur; Barbara Kroczynska; Leonidas C Platanias
Journal:  Cytokine       Date:  2010-04-20       Impact factor: 3.861

Review 4.  The interferons: 50 years after their discovery, there is much more to learn.

Authors:  Sidney Pestka
Journal:  J Biol Chem       Date:  2007-05-14       Impact factor: 5.157

Review 5.  Translational control in cellular and developmental processes.

Authors:  Jian Kong; Paul Lasko
Journal:  Nat Rev Genet       Date:  2012-06       Impact factor: 53.242

6.  Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

Authors:  H B Jefferies; S Fumagalli; P B Dennis; C Reinhard; R B Pearson; G Thomas
Journal:  EMBO J       Date:  1997-06-16       Impact factor: 11.598

7.  The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity.

Authors:  David Shahbazian; Philippe P Roux; Virginie Mieulet; Michael S Cohen; Brian Raught; Jack Taunton; John W B Hershey; John Blenis; Mario Pende; Nahum Sonenberg
Journal:  EMBO J       Date:  2006-06-08       Impact factor: 11.598

8.  Akt phosphorylates and regulates Pdcd4 tumor suppressor protein.

Authors:  Alexey Palamarchuk; Alexey Efanov; Vadim Maximov; Rami I Aqeilan; Carlo M Croce; Yuri Pekarsky
Journal:  Cancer Res       Date:  2005-12-15       Impact factor: 12.701

9.  Dual regulatory roles of phosphatidylinositol 3-kinase in IFN signaling.

Authors:  Surinder Kaur; Antonella Sassano; Ajith M Joseph; Beata Majchrzak-Kita; Elizabeth A Eklund; Amit Verma; Saskia M Brachmann; Eleanor N Fish; Leonidas C Platanias
Journal:  J Immunol       Date:  2008-11-15       Impact factor: 5.422

10.  Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses.

Authors:  Sonali Joshi; Surinder Kaur; Amanda J Redig; Katy Goldsborough; Kevin David; Takeshi Ueda; Rie Watanabe-Fukunaga; Darren P Baker; Eleanor N Fish; Rikiro Fukunaga; Leonidas C Platanias
Journal:  Proc Natl Acad Sci U S A       Date:  2009-07-02       Impact factor: 11.205
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  16 in total

1.  Interferon γ (IFNγ) Signaling via Mechanistic Target of Rapamycin Complex 2 (mTORC2) and Regulatory Effects in the Generation of Type II Interferon Biological Responses.

Authors:  Barbara Kroczynska; Robert L Rafidi; Beata Majchrzak-Kita; Ewa M Kosciuczuk; Gavin T Blyth; Jacek Jemielity; Zofia Warminska; Diana Saleiro; Swarna Mehrotra; Ahmet Dirim Arslan; Eleanor N Fish; Leonidas C Platanias
Journal:  J Biol Chem       Date:  2015-12-08       Impact factor: 5.157

Review 2.  Molecular Aspects of Co-morbidities in COVID-19 Infection.

Authors:  Farzaneh Pouya; Zeynab Imani Saber; Mohammad Amin Kerachian
Journal:  Arch Bone Jt Surg       Date:  2020-04

3.  A precisely positioned MED12 activation helix stimulates CDK8 kinase activity.

Authors:  Felix Klatt; Alexander Leitner; Iana V Kim; Hung Ho-Xuan; Elisabeth V Schneider; Franziska Langhammer; Robin Weinmann; Melanie R Müller; Robert Huber; Gunter Meister; Claus-D Kuhn
Journal:  Proc Natl Acad Sci U S A       Date:  2020-01-27       Impact factor: 11.205

Review 4.  Interferon signaling in cancer. Non-canonical pathways and control of intracellular immune checkpoints.

Authors:  Diana Saleiro; Leonidas C Platanias
Journal:  Semin Immunol       Date:  2019-06       Impact factor: 11.130

5.  Central role of ULK1 in type I interferon signaling.

Authors:  Diana Saleiro; Swarna Mehrotra; Barbara Kroczynska; Elspeth M Beauchamp; Pawel Lisowski; Beata Majchrzak-Kita; Tushar D Bhagat; Brady L Stein; Brandon McMahon; Jessica K Altman; Ewa M Kosciuczuk; Darren P Baker; Chunfa Jie; Nadereh Jafari; Craig B Thompson; Ross L Levine; Eleanor N Fish; Amit K Verma; Leonidas C Platanias
Journal:  Cell Rep       Date:  2015-04-16       Impact factor: 9.423

6.  Central Regulatory Role for SIN1 in Interferon γ (IFNγ) Signaling and Generation of Biological Responses.

Authors:  Barbara Kroczynska; Gavin T Blyth; Robert L Rafidi; Beata Majchrzak-Kita; Lucy Xu; Diana Saleiro; Ewa M Kosciuczuk; Jacek Jemielity; Bing Su; Jessica K Altman; Elizabeth A Eklund; Eleanor N Fish; Leonidas C Platanias
Journal:  J Biol Chem       Date:  2017-02-07       Impact factor: 5.157

7.  miR-145 and miR20a-5p Potentially Mediate Pleiotropic Effects of Interferon-Beta Through Mitogen-Activated Protein Kinase Signaling Pathway in Multiple Sclerosis Patients.

Authors:  Naeim Ehtesham; Fariborz Khorvash; Majid Kheirollahi
Journal:  J Mol Neurosci       Date:  2016-10-17       Impact factor: 3.444

8.  Zika Virus Targets Human STAT2 to Inhibit Type I Interferon Signaling.

Authors:  Alesha Grant; Sanket S Ponia; Shashank Tripathi; Vinod Balasubramaniam; Lisa Miorin; Marion Sourisseau; Megan C Schwarz; Mari Paz Sánchez-Seco; Matthew J Evans; Sonja M Best; Adolfo García-Sastre
Journal:  Cell Host Microbe       Date:  2016-05-19       Impact factor: 21.023

9.  Interferon-γ regulates cellular metabolism and mRNA translation to potentiate macrophage activation.

Authors:  Xiaodi Su; Yingpu Yu; Yi Zhong; Eugenia G Giannopoulou; Xiaoyu Hu; Hui Liu; Justin R Cross; Gunnar Rätsch; Charles M Rice; Lionel B Ivashkiv
Journal:  Nat Immunol       Date:  2015-06-29       Impact factor: 25.606

Review 10.  No Love Lost Between Viruses and Interferons.

Authors:  Volker Fensterl; Saurabh Chattopadhyay; Ganes C Sen
Journal:  Annu Rev Virol       Date:  2015-09-25       Impact factor: 14.263
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