Literature DB >> 18163952

The interferon signaling network and transcription factor C/EBP-beta.

Hui Li1, Padmaja Gade, Weihua Xiao, Dhan V Kalvakolanu.   

Abstract

Cytokines like interferons (IFNs) play a central role in regulating innate and specific immunities against the pathogens and neoplastic cells. A number of signaling pathways are induced in response to IFN in various cells. One classic mechanism employed by IFNs is the JAK-STAT signaling pathway for inducing cellular responses. Here we describe the non-STAT pathways that participate in IFN-induced responses. In particular, we will focus on the role played by transcription factor C/EBP-beta in mediating these responses.

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Year:  2007        PMID： 18163952      PMCID： PMC2782719     

Source DB:  PubMed          Journal:  Cell Mol Immunol        ISSN： 1672-7681            Impact factor:   11.530


  155 in total

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