PURPOSE: To prospectively evaluate the effect of single- versus two-segment image reconstruction on image quality and diagnostic accuracy at 64-section multidetector computed tomographic (CT) coronary angiography by using conventional coronary angiography as the reference standard. MATERIALS AND METHODS: The study design was approved by a human research committee; patients gave informed consent. The study was HIPAA compliant. Forty consecutive patients (22 men, 18 women; mean age, 61 years +/- 8 [standard deviation]) underwent both 64-section multidetector CT coronary angiography and conventional angiography. All data sets were reconstructed by using single- and two-segment image reconstruction algorithms, with resulting temporal resolution of 82.5-165 msec. Two experienced observers independently evaluated image quality and signs of coronary artery disease. A five-level grading scheme was used to grade stenosis (0%, <50%, <70%, <99%, 100%) and image quality (1[unacceptable] to 5[excellent]). Interobserver correlation, Spearman correlation coefficients, and diagnostic accuracy were calculated. RESULTS: Six hundred coronary artery segments were visible on conventional angiograms, of which 560 (93.3%) were seen by using single-segment and 561 (93.5%) were seen by using two-segment image reconstruction (P=.35). Mean quality scores were not significantly different (P=.22) for single- (3.1 +/- 0.9) and two-segment (3.2 +/- 0.8) reconstruction. Significantly (P=.03) better image quality was observed for two-segment reconstruction only at heart rates of 80-82 beats per minute, at which temporal resolution was approximately 83 msec. For grading coronary artery stenosis, correlation was 0.64 for single- and 0.66 for two-segment reconstruction (P=.43). Significant stenosis (>50%) was detected on a per-segment basis with 77.1% sensitivity and 98.6% specificity by using single-segment and with 79.2% sensitivity and 99.1% specificity by using two-segment image reconstruction. CONCLUSION: At heart rates of more than 65 beats per minute, use of two-segment reconstruction improves image quality at multidetector CT coronary angiography but does not significantly affect overall diagnostic accuracy compared with single-segment reconstruction. (c) RSNA, 2007.
PURPOSE: To prospectively evaluate the effect of single- versus two-segment image reconstruction on image quality and diagnostic accuracy at 64-section multidetector computed tomographic (CT) coronary angiography by using conventional coronary angiography as the reference standard. MATERIALS AND METHODS: The study design was approved by a human research committee; patients gave informed consent. The study was HIPAA compliant. Forty consecutive patients (22 men, 18 women; mean age, 61 years +/- 8 [standard deviation]) underwent both 64-section multidetector CT coronary angiography and conventional angiography. All data sets were reconstructed by using single- and two-segment image reconstruction algorithms, with resulting temporal resolution of 82.5-165 msec. Two experienced observers independently evaluated image quality and signs of coronary artery disease. A five-level grading scheme was used to grade stenosis (0%, <50%, <70%, <99%, 100%) and image quality (1[unacceptable] to 5[excellent]). Interobserver correlation, Spearman correlation coefficients, and diagnostic accuracy were calculated. RESULTS: Six hundred coronary artery segments were visible on conventional angiograms, of which 560 (93.3%) were seen by using single-segment and 561 (93.5%) were seen by using two-segment image reconstruction (P=.35). Mean quality scores were not significantly different (P=.22) for single- (3.1 +/- 0.9) and two-segment (3.2 +/- 0.8) reconstruction. Significantly (P=.03) better image quality was observed for two-segment reconstruction only at heart rates of 80-82 beats per minute, at which temporal resolution was approximately 83 msec. For grading coronary artery stenosis, correlation was 0.64 for single- and 0.66 for two-segment reconstruction (P=.43). Significant stenosis (>50%) was detected on a per-segment basis with 77.1% sensitivity and 98.6% specificity by using single-segment and with 79.2% sensitivity and 99.1% specificity by using two-segment image reconstruction. CONCLUSION: At heart rates of more than 65 beats per minute, use of two-segment reconstruction improves image quality at multidetector CT coronary angiography but does not significantly affect overall diagnostic accuracy compared with single-segment reconstruction. (c) RSNA, 2007.
Authors: John H Nichols; Bharat Samy; Khurram Nasir; Caroline S Fox; P Christian Schulze; Fabian Bamberg; Udo Hoffmann Journal: J Cardiovasc Comput Tomogr Date: 2008-08-19
Authors: Frank J Rybicki; Hansel J Otero; Michael L Steigner; Gabriel Vorobiof; Leelakrishna Nallamshetty; Dimitrios Mitsouras; Hale Ersoy; Richard T Mather; Philip F Judy; Tianxi Cai; Karl Coyner; Kurt Schultz; Amanda G Whitmore; Marcelo F Di Carli Journal: Int J Cardiovasc Imaging Date: 2008-03-27 Impact factor: 2.357