Literature DB >> 17477649

Induction charge detector with multiple sensing stages.

Manuel Gamero-Castaño1.   

Abstract

An induction charge detector yields the net charge and the time of flight of a particle. The unique ability to independently measure these two parameters sets apart this rather simple detection technique. The main shortcoming of this instrument is its high charge detection limit, resulting from the intrinsic noise of the detector electronics and the low signal associated with the charge to measure. The goal of the present work is to lower the detection limit of this detector. This article describes an induction charge detector whose main novelty is a sequence of aligned cylindrical electrodes for measuring the charge of a particle n times. In a time domain analysis, this feature reduces both the detection limit and the standard error of the charge measurement by factors of square root of 2 and square root of n. More importantly, sensing stages could be added to arbitrarily lower the detection limit in a frequency domain analysis.

Mesh:

Year:  2007        PMID: 17477649     DOI: 10.1063/1.2721408

Source DB:  PubMed          Journal:  Rev Sci Instrum        ISSN: 0034-6748            Impact factor:   1.523


  10 in total

1.  Charge Detection Mass Spectrometry Identifies Preferred Non-Icosahedral Polymorphs in the Self-Assembly of Woodchuck Hepatitis Virus Capsids.

Authors:  Elizabeth E Pierson; David Z Keifer; Alexander A Kukreja; Joseph C-Y Wang; Adam Zlotnick; Martin F Jarrold
Journal:  J Mol Biol       Date:  2015-07-04       Impact factor: 5.469

2.  Charge Detection Mass Spectrometry for Single Ions with an Uncertainty in the Charge Measurement of 0.65 e.

Authors:  Elizabeth E Pierson; Nathan C Contino; David Z Keifer; Martin F Jarrold
Journal:  J Am Soc Mass Spectrom       Date:  2015-04-14       Impact factor: 3.109

3.  A Miniaturized Fourier Transform Electrostatic Linear Ion Trap Mass Spectrometer: Mass Range and Resolution.

Authors:  Joshua T Johnson; Kenneth W Lee; Jay S Bhanot; Scott A McLuckey
Journal:  J Am Soc Mass Spectrom       Date:  2019-02-12       Impact factor: 3.109

4.  Effects of Individual Ion Energies on Charge Measurements in Fourier Transform Charge Detection Mass Spectrometry (FT-CDMS).

Authors:  Andrew G Elliott; Conner C Harper; Haw-Wei Lin; Evan R Williams
Journal:  J Am Soc Mass Spectrom       Date:  2018-11-14       Impact factor: 3.109

5.  Charge detection mass spectrometry with resolved charge states.

Authors:  Nathan C Contino; Elizabeth E Pierson; David Z Keifer; Martin F Jarrold
Journal:  J Am Soc Mass Spectrom       Date:  2012-11-30       Impact factor: 3.109

6.  Single Particle Analyzer of Mass: A Charge Detection Mass Spectrometer with a Multi-Detector Electrostatic Ion Trap.

Authors:  Andrew G Elliott; Samuel I Merenbloom; Satrajit Chakrabarty; Evan R Williams
Journal:  Int J Mass Spectrom       Date:  2017-01-15       Impact factor: 1.986

7.  Acquiring Structural Information on Virus Particles with Charge Detection Mass Spectrometry.

Authors:  David Z Keifer; Tina Motwani; Carolyn M Teschke; Martin F Jarrold
Journal:  J Am Soc Mass Spectrom       Date:  2016-03-28       Impact factor: 3.109

8.  Charge detection mass spectrometry of bacteriophage P22 procapsid distributions above 20 MDa.

Authors:  David Z Keifer; Elizabeth E Pierson; Joanna A Hogan; Gregory J Bedwell; Peter E Prevelige; Martin F Jarrold
Journal:  Rapid Commun Mass Spectrom       Date:  2014-03-15       Impact factor: 2.419

9.  Dramatic Improvement in Sensitivity with Pulsed Mode Charge Detection Mass Spectrometry.

Authors:  Aaron R Todd; Martin F Jarrold
Journal:  Anal Chem       Date:  2019-10-07       Impact factor: 6.986

10.  Detection of small bunches of ions using image charges.

Authors:  Paul Räcke; Daniel Spemann; Jürgen W Gerlach; Bernd Rauschenbach; Jan Meijer
Journal:  Sci Rep       Date:  2018-06-28       Impact factor: 4.379

  10 in total

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