Literature DB >> 17458506

Hypoxia, gene expression, and metastasis.

Denise A Chan1, Amato J Giaccia.   

Abstract

Hypoxia poses many problems to the treatment of cancer. Hypoxic tumors are more resistant to chemotherapy and radiation. In addition, hypoxia induces a number of genes responsible for increased invasion, aggressiveness, and metastasis of tumors. The augmented metastatic potential due to hypoxia-mediated gene expression is discussed in this section. Particular attention is given to recent studies of specific genes involved in the key steps of metastasis, including extracellular matrix interactions, migration, and proliferation.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17458506     DOI： 10.1007/s10555-007-9063-1

Source DB:  PubMed          Journal:  Cancer Metastasis Rev        ISSN： 0167-7659            Impact factor:   9.264


  121 in total

Review 1.  Hypoxia-inducible factors in physiology and medicine.

Authors:  Gregg L Semenza
Journal:  Cell       Date:  2012-02-03       Impact factor: 41.582

2.  Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer.

Authors:  Yoshinaga Okugawa; Yuji Toiyama; Shusuke Toden; Hiroki Mitoma; Takeshi Nagasaka; Koji Tanaka; Yasuhiro Inoue; Masato Kusunoki; C Richard Boland; Ajay Goel
Journal:  Gut       Date:  2015-10-15       Impact factor: 23.059

3.  Long-term interferon-α treatment suppresses tumor growth but promotes metastasis capacity in hepatocellular carcinoma.

Authors:  Peng-Yuan Zhuang; Ju-Bo Zhang; Wei Zhang; Xiao-Dong Zhu; Ying Liang; Hua-Xiang Xu; Yu-Quan Xiong; Ling-Qun Kong; Lu Wang; Wei-Zhong Wu; Zhao-You Tang; Lun-Xiu Qin; Hui-Chuan Sun
Journal:  J Cancer Res Clin Oncol       Date:  2010-03-06       Impact factor: 4.553

Review 4.  Imaging tumor hypoxia to advance radiation oncology.

Authors:  Chen-Ting Lee; Mary-Keara Boss; Mark W Dewhirst
Journal:  Antioxid Redox Signal       Date:  2014-03-24       Impact factor: 8.401

Review 5.  Defining normoxia, physoxia and hypoxia in tumours-implications for treatment response.

Authors:  S R McKeown
Journal:  Br J Radiol       Date:  2014-03       Impact factor: 3.039

6.  High oxygen condition facilitates the differentiation of mouse and human pluripotent stem cells into pancreatic progenitors and insulin-producing cells.

Authors:  Farzana Hakim; Taku Kaitsuka; Jamiruddin Mohd Raeed; Fan-Yan Wei; Nobuaki Shiraki; Tadayuki Akagi; Takashi Yokota; Shoen Kume; Kazuhito Tomizawa
Journal:  J Biol Chem       Date:  2014-02-19       Impact factor: 5.157

Review 7.  Molecular imaging to guide systemic cancer therapy: Illustrative examples of PET imaging cancer biomarkers.

Authors:  Austin R Pantel; David A Mankoff
Journal:  Cancer Lett       Date:  2016-05-16       Impact factor: 8.679

8.  Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation.

Authors:  Xin Huang; Lianghao Ding; Kevin L Bennewith; Ricky T Tong; Scott M Welford; K Kian Ang; Michael Story; Quynh-Thu Le; Amato J Giaccia
Journal:  Mol Cell       Date:  2009-09-24       Impact factor: 17.970

9.  Short hairpin RNA interference therapy for ischemic heart disease.

Authors:  Mei Huang; Denise A Chan; Fangjun Jia; Xiaoyan Xie; Zongjin Li; Grant Hoyt; Robert C Robbins; Xiaoyuan Chen; Amato J Giaccia; Joseph C Wu
Journal:  Circulation       Date:  2008-09-30       Impact factor: 29.690

10.  Meta-analysis of archived DNA microarrays identifies genes regulated by hypoxia and involved in a metastatic phenotype in cancer cells.

Authors:  Michael Pierre; Benoît DeHertogh; Anthoula Gaigneaux; Bertrand DeMeulder; Fabrice Berger; Eric Bareke; Carine Michiels; Eric Depiereux
Journal:  BMC Cancer       Date:  2010-04-30       Impact factor: 4.430
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.