Literature DB >> 17445181

KIR receptors and HLA-C in the maintenance of pregnancy.

A C Flores1, C Y Marcos, N Paladino, L Arruvito, F Williams, D Middleton, L Fainboim.   

Abstract

The present study demonstrated that patients who have recurrent spontaneous abortions (RSA) presented a decreased number of killer immunoglobulin-like inhibitory receptors (KIR), in particular KIR2DL2. The KIR AA genotype was found increased in comparison with controls. Individuals AA will also be homozygous for 2DL3, which in contrast to 2DL2, show a weaker interaction with C1 ligands and therefore a weaker inhibition. The present study might support that in RSA patients, the balance between inhibitory and activating receptors present in natural killer cells is inclined toward an activating state that may contribute to pregnancy loss.

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Year:  2007        PMID： 17445181     DOI： 10.1111/j.1399-0039.2006.762_8.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN： 0001-2815


  9 in total

1.  Evaluation of KIR genes in recurrent miscarriage.

Authors:  Ozlem Goruroglu Ozturk; Gulhan Sahın; Esin Damla Zıyanoglu Karacor; Umran Kucukgoz
Journal:  J Assist Reprod Genet       Date:  2012-06-06       Impact factor: 3.412

Review 2.  Understanding the role of killer cell immunoglobulin-like receptors in pregnancy complications.

Authors:  R Díaz-Peña; M J de Los Santos; Alejandro Lucia; P Castro-Santos
Journal:  J Assist Reprod Genet       Date:  2019-03-07       Impact factor: 3.412

3.  Persistence of decidual NK cells and KIR genotypes in healthy pregnant and preeclamptic women: a case-control study in the third trimester of gestation.

Authors:  Elly N Sánchez-Rodríguez; Sonia Nava-Salazar; C Adriana Mendoza-Rodríguez; Carlos Moran; Juan F Romero-Arauz; Enrique Ortega; Julio Granados; Alicia Cervantes-Peredo; Marco Cerbón
Journal:  Reprod Biol Endocrinol       Date:  2011-01-19       Impact factor: 5.211

Review 4.  The role of KIR and HLA interactions in pregnancy complications.

Authors:  Francesco Colucci
Journal:  Immunogenetics       Date:  2017-07-10       Impact factor: 2.846

5.  Genomic Analysis of Spontaneous Abortion in Holstein Heifers and Primiparous Cows.

Authors:  Kayleen F Oliver; Alexandria M Wahl; Mataya Dick; Jewel A Toenges; Jennifer N Kiser; Justine M Galliou; Joao G N Moraes; Gregory W Burns; Joseph Dalton; Thomas E Spencer; Holly L Neibergs
Journal:  Genes (Basel)       Date:  2019-11-21       Impact factor: 4.096

6.  KIR- Ligand Interactions in Hypertensive Disorders in Pregnancy.

Authors:  Katarzyna Stefańska; Martyna Tomaszewicz; Joanna Dębska-Zielkowska; Dorota Zamkowska; Karolina Piekarska; Justyna Sakowska; Maciej Studziński; Bogusław Tymoniuk; Przemysław Adamski; Joanna Jassem-Bobowicz; Piotr Wydra; Katarzyna Leszczyńska; Renata Świątkowska-Stodulska; Sebastian Kwiatkowski; Krzysztof Preis; Piotr Trzonkowski; Natalia Marek-Trzonkowska; Maciej Zieliński
Journal:  Front Immunol       Date:  2022-07-15       Impact factor: 8.786

7.  Killer cell immunoglobulin-like receptor gene associations with autoimmune and allergic diseases, recurrent spontaneous abortion, and neoplasms.

Authors:  Piotr Kuśnierczyk
Journal:  Front Immunol       Date:  2013-01-29       Impact factor: 7.561

8.  Paternal HLA-C and Maternal Killer-Cell Immunoglobulin-Like Receptor Genotypes in the Development of Autism.

Authors:  Moriya Gamliel; Karen L Anderson; Richard P Ebstein; Nurit Yirmiya; David Mankuta
Journal:  Front Pediatr       Date:  2016-07-28       Impact factor: 3.418

9.  Maternal natural killer cell immunoglobulin receptor genes and human leukocyte antigen-C ligands influence recurrent spontaneous abortion in the Han Chinese population.

Authors:  Ning Su; Hongdan Wang; Bowei Zhang; Yiqing Kang; Qiannan Guo; Hai Xiao; Hecai Yang; Shixiu Liao
Journal:  Exp Ther Med       Date:  2017-10-31       Impact factor: 2.447
  9 in total

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