Literature DB >> 17438044

Association between embB codon 306 mutations and drug resistance in Mycobacterium tuberculosis.

Xin Shen1, Guo-miao Shen, Jie Wu, Xiao-hong Gui, Xia Li, Jian Mei, Kathryn DeRiemer, Qian Gao.   

Abstract

embB306 mutants were detected in both ethambutol (EMB)-resistant and EMB-susceptible strains of Mycobacterium tuberculosis. Multidrug-resistant (MDR) strains had a higher proportion of embB306 mutants than non-MDR strains (odds ratio, 6.78; P < 0.001). The embB306 locus is a candidate marker for rapid detection of MDR and extremely drug resistant tuberculosis.

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Year:  2007        PMID： 17438044      PMCID： PMC1913254          DOI： 10.1128/AAC.01516-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Ethambutol resistance in Mycobacterium tuberculosis: critical role of embB mutations.

Authors:  S Sreevatsan; K E Stockbauer; X Pan; B N Kreiswirth; S L Moghazeh; W R Jacobs; A Telenti; J M Musser
Journal:  Antimicrob Agents Chemother       Date:  1997-08       Impact factor: 5.191

2.  Molecular genetic analysis of nucleotide polymorphisms associated with ethambutol resistance in human isolates of Mycobacterium tuberculosis.

Authors:  S V Ramaswamy; A G Amin; S Göksel; C E Stager; S J Dou; H El Sahly; S L Moghazeh; B N Kreiswirth; J M Musser
Journal:  Antimicrob Agents Chemother       Date:  2000-02       Impact factor: 5.191

3.  Novel mutations within the embB gene in ethambutol-susceptible clinical isolates of Mycobacterium tuberculosis.

Authors:  Ann S G Lee; Siti Noor Khadijah Othman; Yu Min Ho; Sin Yew Wong
Journal:  Antimicrob Agents Chemother       Date:  2004-11       Impact factor: 5.191

4.  Evaluation of the epidemiologic utility of secondary typing methods for differentiation of Mycobacterium tuberculosis isolates.

Authors:  Awewura Kwara; Ronald Schiro; Lauren S Cowan; Newton E Hyslop; Mark F Wiser; Stephanie Roahen Harrison; Patricia Kissinger; Lois Diem; Jack T Crawford
Journal:  J Clin Microbiol       Date:  2003-06       Impact factor: 5.948

5.  The emb operon, a gene cluster of Mycobacterium tuberculosis involved in resistance to ethambutol.

Authors:  A Telenti; W J Philipp; S Sreevatsan; C Bernasconi; K E Stockbauer; B Wieles; J M Musser; W R Jacobs
Journal:  Nat Med       Date:  1997-05       Impact factor: 53.440

6.  Development of a pyrosequencing approach for rapid screening of rifampin, isoniazid and ethambutol-resistant Mycobacterium tuberculosis.

Authors:  J-R Zhao; Y-J Bai; Y Wang; Q-H Zhang; M Luo; X-J Yan
Journal:  Int J Tuberc Lung Dis       Date:  2005-03       Impact factor: 2.373

7.  Standard short-course chemotherapy for drug-resistant tuberculosis: treatment outcomes in 6 countries.

Authors:  M A Espinal; S J Kim; P G Suarez; K M Kam; A G Khomenko; G B Migliori; J Baéz; A Kochi; C Dye; M C Raviglione
Journal:  JAMA       Date:  2000-05-17       Impact factor: 56.272

8.  Role of embB in natural and acquired resistance to ethambutol in mycobacteria.

Authors:  F Alcaide; G E Pfyffer; A Telenti
Journal:  Antimicrob Agents Chemother       Date:  1997-10       Impact factor: 5.191

9.  A single point mutation in the embB gene is responsible for resistance to ethambutol in Mycobacterium smegmatis.

Authors:  M A Lety; S Nair; P Berche; V Escuyer
Journal:  Antimicrob Agents Chemother       Date:  1997-12       Impact factor: 5.191

10.  Detection of embB306 mutations in ethambutol-susceptible clinical isolates of Mycobacterium tuberculosis from Northwestern Russia: implications for genotypic resistance testing.

Authors:  Igor Mokrousov; Tatiana Otten; Boris Vyshnevskiy; Olga Narvskaya
Journal:  J Clin Microbiol       Date:  2002-10       Impact factor: 5.948
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  19 in total

1.  Multiplex real-time PCR melting curve assay to detect drug-resistant mutations of Mycobacterium tuberculosis.

Authors:  Tao Luo; Lili Jiang; Weiming Sun; G Fu; Jian Mei; Qian Gao
Journal:  J Clin Microbiol       Date:  2011-07-13       Impact factor: 5.948

2.  Molecular Analysis of the embCAB Locus and embR Gene Involved in Ethambutol Resistance in Clinical Isolates of Mycobacterium tuberculosis in France.

Authors:  Florence Brossier; Wladimir Sougakoff; Christine Bernard; Matthieu Petrou; Karine Adeyema; Anne Pham; Diane Amy de la Breteque; Marine Vallet; Vincent Jarlier; Christophe Sola; Nicolas Veziris
Journal:  Antimicrob Agents Chemother       Date:  2015-06-01       Impact factor: 5.191

3.  Mycobacterium tuberculosis embB codon 306 mutations confer moderately increased resistance to ethambutol in vitro and in vivo.

Authors:  Claudia Plinke; Kerstin Walter; Sahar Aly; Stefan Ehlers; Stefan Niemann
Journal:  Antimicrob Agents Chemother       Date:  2011-03-28       Impact factor: 5.191

4.  Pyrosequencing analysis for mutations in embB codon306 among clinical mycobacterium tuberculosis isolates from Qingdao, China.

Authors:  Huaqiang Zhang; Xiaoguang Chen; Zhongdong Wang; Zhisheng Ren; Jie Wu; Haiyan Sun; Xue Bai
Journal:  Int J Clin Exp Med       Date:  2015-07-15

5.  Performance Assessment of the Polymerase Chain Reaction-Restriction Fragment Length Polymorphism Method for Rapid Detection of Susceptibility to Ethambutol and Molecular Prediction of Extensively Drug-resistant Tuberculosis in Clinical Isolates of Mycobacterium tuberculosis.

Authors:  M Arjomandzadegan; R Nazari; M R Zolfaghari; M Taherahmadi; M Sadrnia; L P Titov; A Ahmadi; M Shojapoor
Journal:  West Indian Med J       Date:  2015-06-12       Impact factor: 0.171

6.  Mutation at embB codon 306, a potential marker for the identification of multidrug resistance associated with ethambutol in Mycobacterium tuberculosis.

Authors:  Betzaida Cuevas-Córdoba; Dulce María Juárez-Eusebio; Raquel Almaraz-Velasco; Raquel Muñiz-Salazar; Rafael Laniado-Laborin; Roberto Zenteno-Cuevas
Journal:  Antimicrob Agents Chemother       Date:  2015-06-29       Impact factor: 5.191

7.  Selection of mutations to detect multidrug-resistant Mycobacterium tuberculosis strains in Shanghai, China.

Authors:  Tao Luo; Ming Zhao; Xia Li; Peng Xu; Xiaohong Gui; Sam Pickerill; Kathryn DeRiemer; Jian Mei; Qian Gao
Journal:  Antimicrob Agents Chemother       Date:  2009-12-14       Impact factor: 5.191

8.  Association between embB Codon 306 Mutations, Phenotypic Resistance Profiles, and Genotypic Characterization in Clinical Mycobacterium tuberculosis Isolates from Hebei, China.

Authors:  Yanan Li; Yuling Wang; Zhi Zhang; Huixia Gao; Haibin Wang; Jinfeng Cao; Shumin Zhang; Yuzhen Liu; Jianhua Lu; Zungui Xu; Erhei Dai
Journal:  Antimicrob Agents Chemother       Date:  2016-11-21       Impact factor: 5.191

9.  Convergent evolutionary analysis identifies significant mutations in drug resistance targets of Mycobacterium tuberculosis.

Authors:  Manzour Hernando Hazbón; Alifiya S Motiwala; Magali Cavatore; Michael Brimacombe; Thomas S Whittam; David Alland
Journal:  Antimicrob Agents Chemother       Date:  2008-06-30       Impact factor: 5.191

10.  Mutations at embB codon 306 are an important molecular indicator of ethambutol resistance in Mycobacterium tuberculosis.

Authors:  Angela M Starks; Aysel Gumusboga; Bonnie B Plikaytis; Thomas M Shinnick; James E Posey
Journal:  Antimicrob Agents Chemother       Date:  2008-12-22       Impact factor: 5.191
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