Literature DB >> 17429658

Posterior fossa tumors in children: how long does it take to establish the diagnosis?

Lutz Dörner1, Michael J Fritsch, Andreas M Stark, Hubertus Maximilian Mehdorn.   

Abstract

OBJECTIVE: The aim of this study is to evaluate, for our patient population, the time interval from the first chart-documented symptom to the radiological diagnosis in children and infants with posterior fossa tumors.
MATERIALS AND METHODS: We retrospectively analyzed 50 consecutive children (36 men, 14 women) with posterior fossa tumor treated at our department between January 1999 and December 2003. The mean age at time of diagnosis was 98 months (6 months-16 years). The mean follow up was 27 months (6-61 months). The diagnoses included astrocytoma (n = 17), medulloblastoma (n = 15), ependymoma (n = 6), and other tumors (n = 12).
RESULTS: The mean time interval between onset of symptoms and radiographic diagnosis was 142 days (5-535 days), the median was 59 days. The mean time for Grade I and II tumors was 238 days (n = 19) and for tumors Grade III and IV 117 days (n = 31). The most common presenting symptoms were headache, nausea, vomiting, ataxia, and oculomotor deficits. Approximately half of the patients were initially diagnosed and treated for other diseases (gastrointestinal infection, appendicitis, psychological behavioral problems, cervical spine strains, different ophthalmologic entities). Specialists (ophthalmologists, orthopedics) tended to diagnose and treat their specific diagnoses (e.g., strabism, torticollis). Parents play a significant role in the process of establishing the correct diagnosis.
CONCLUSION: We conclude that further information and education regarding symptomatology and diagnosis of posterior fossa tumors in children is necessary. Communication has to be improved between parents and referring physicians of all specialties and neurosurgeons.

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Year:  2007        PMID: 17429658     DOI: 10.1007/s00381-007-0323-8

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  9 in total

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2.  Acquired torticollis as the only presenting symptom in children with posterior fossa tumors.

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Journal:  J Pediatr Orthop       Date:  1996 Jul-Aug       Impact factor: 2.324

  9 in total
  17 in total

1.  Child-related characteristics predicting subsequent health-related quality of life in 8- to 14-year-old children with and without cerebellar tumors: a prospective longitudinal study.

Authors:  Kim S Bull; Christina Liossi; David Culliford; Janet L Peacock; Colin R Kennedy
Journal:  Neurooncol Pract       Date:  2014-08-11

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Authors:  Aska Arnautovic; Catherine Billups; Alberto Broniscer; Amar Gajjar; Frederick Boop; Ibrahim Qaddoumi
Journal:  Childs Nerv Syst       Date:  2015-03-06       Impact factor: 1.475

3.  Torticollis as a first sign of posterior fossa and cervical spinal cord tumors in children.

Authors:  Alicja Fąfara-Leś; Stanisław Kwiatkowski; Laura Maryńczak; Zdzisław Kawecki; Dariusz Adamek; Izabela Herman-Sucharska; Krzysztof Kobylarz
Journal:  Childs Nerv Syst       Date:  2013-08-18       Impact factor: 1.475

4.  Time to diagnosis of pediatric brain tumors: a report from the Pediatric Hematology and Oncology Center in Rabat, Morocco.

Authors:  Fatima Zahra Boutahar; Sarra Benmiloud; Maria El Kababri; Amina Kili; Mohamed El Khorassani; Nazik Allali; Mohamed Khattab; Ibrahim Qaddoumi; Laila Hessissen
Journal:  Childs Nerv Syst       Date:  2018-07-27       Impact factor: 1.475

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Authors:  Vered Shay; Aviva Fattal-Valevski; Liana Beni-Adani; Shlomi Constantini
Journal:  Childs Nerv Syst       Date:  2011-08-26       Impact factor: 1.475

6.  Progression from first symptom to diagnosis in childhood brain tumours.

Authors:  Sophie Wilne; Jacqueline Collier; Colin Kennedy; Anna Jenkins; Joanne Grout; Shona Mackie; Karin Koller; Richard Grundy; David Walker
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7.  Posterior cranial fossa tumours in children at National Cancer Institute, Sudan: a single institution experience.

Authors:  Moawia Mohammed Ali Elhassan; Haytham Hussein Mohammed Osman; Jeannette Parkes
Journal:  Childs Nerv Syst       Date:  2017-04-21       Impact factor: 1.475

Review 8.  Neuroimaging in childhood headache: a systematic review.

Authors:  George A Alexiou; Maria I Argyropoulou
Journal:  Pediatr Radiol       Date:  2013-05-23

9.  Different etiologies of acquired torticollis in childhood.

Authors:  Hüseyin Per; Mehmet Canpolat; Abdülfettah Tümtürk; Hakan Gumuş; Abdulkerim Gokoglu; Ali Yikilmaz; Sevgi Özmen; Ayşe Kaçar Bayram; Hatice Gamze Poyrazoğlu; Sefer Kumandas; Ali Kurtsoy
Journal:  Childs Nerv Syst       Date:  2013-11-06       Impact factor: 1.475

Review 10.  Case-based review: pediatric medulloblastoma.

Authors:  Cassie N Kline; Roger J Packer; Eugene I Hwang; David R Raleigh; Steve Braunstein; Corey Raffel; Pratiti Bandopadhayay; David A Solomon; Mariam Aboian; Soonmee Cha; Sabine Mueller
Journal:  Neurooncol Pract       Date:  2017-08-11
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