Literature DB >> 30054805

Time to diagnosis of pediatric brain tumors: a report from the Pediatric Hematology and Oncology Center in Rabat, Morocco.

Fatima Zahra Boutahar1, Sarra Benmiloud2, Maria El Kababri3, Amina Kili3, Mohamed El Khorassani3, Nazik Allali4, Mohamed Khattab3, Ibrahim Qaddoumi5, Laila Hessissen6.   

Abstract

OBJECTIVE: Delayed diagnosis of pediatric brain tumors is known to occur worldwide but is not well studied in developing countries. Here, we examined the extent of delayed pediatric brain tumor diagnoses in Rabat, Morocco, and consider its potential causes and possible solutions.
METHODS: We conducted a survey and interviews of the parents of children who were admitted to the Department of Hematology and Pediatric Oncology of Rabat Children's Hospital from January 1, 2016 to June 30, 2016.
RESULTS: The families of 27 patients (14 girls and 13 boys) participated in the survey and interview. The median patient age was 7 years (range, 1-15 years). The most common presenting symptoms were vomiting (n = 18) and headache (n = 17). The tumor locations were supratentorial in 13 cases and infratentorial in 14 cases. The median time to diagnosis was 2 months (range, 0.25-20 months). The longest times to diagnosis occurred in children older than 5 years and in patients with supratentorial tumors or low-grade glioma. We did not observe any differences in the time to diagnosis according to sex, socioeconomic status, or urban or rural origin.
CONCLUSIONS: Delayed diagnosis of pediatric brain tumors is a universal problem, evidenced by many studies in different countries. We propose that a paradigm shift in medical curricula addressing the delayed diagnosis of pediatric brain tumors should occur in medical schools and clinical training programs.

Entities:  

Keywords:  Brain neoplasms; Child; Delayed diagnosis; Intracranial hypertension

Mesh:

Year:  2018        PMID: 30054805     DOI: 10.1007/s00381-018-3927-2

Source DB:  PubMed          Journal:  Childs Nerv Syst        ISSN: 0256-7040            Impact factor:   1.475


  32 in total

1.  Parents' accounts of obtaining a diagnosis of childhood cancer.

Authors:  M Dixon-Woods; M Findlay; B Young; H Cox; D Heney
Journal:  Lancet       Date:  2001-03-03       Impact factor: 79.321

2.  [Care pathways before diagnosis in children and adolescents with malignancies].

Authors:  Sarah Tatencloux; Véronique Mosseri; Solesne Papillard-Maréchal; Bettina Mesples; Beatrice Pellegrino; Marie Belloy; Irene Jimènez; Nathalie Algret; Dominique Levy; Jean Michon; Daniel Orbach
Journal:  Bull Cancer       Date:  2016-12-07       Impact factor: 1.276

3.  Metastasis stage, adjuvant treatment, and residual tumor are prognostic factors for medulloblastoma in children: conclusions from the Children's Cancer Group 921 randomized phase III study.

Authors:  P M Zeltzer; J M Boyett; J L Finlay; A L Albright; L B Rorke; J M Milstein; J C Allen; K R Stevens; P Stanley; H Li; J H Wisoff; J R Geyer; P McGuire-Cullen; J A Stehbens; S B Shurin; R J Packer
Journal:  J Clin Oncol       Date:  1999-03       Impact factor: 44.544

4.  Children with brain tumor headaches. Distinguishing features.

Authors:  P J Honig; E B Charney
Journal:  Am J Dis Child       Date:  1982-02

Review 5.  Epidemiological features of brain tumors in the first 3 years of life.

Authors:  C H Rickert
Journal:  Childs Nerv Syst       Date:  1998-10       Impact factor: 1.475

6.  Delay in the diagnosis of paediatric brain tumours.

Authors:  Milana Dobrovoljac; Heinz Hengartner; Eugen Boltshauser; Michael A Grotzer
Journal:  Eur J Pediatr       Date:  2002-11-08       Impact factor: 3.183

7.  Interval between symptom onset and diagnosis of pediatric solid tumors.

Authors:  B H Pollock; J P Krischer; T J Vietti
Journal:  J Pediatr       Date:  1991-11       Impact factor: 4.406

8.  Outcome and prognostic features in pediatric gliomas: a review of 6212 cases from the Surveillance, Epidemiology, and End Results database.

Authors:  Ibrahim Qaddoumi; Iyad Sultan; Amar Gajjar
Journal:  Cancer       Date:  2009-12-15       Impact factor: 6.860

9.  Prognostic factors and treatment results for supratentorial primitive neuroectodermal tumors in children using radiation and chemotherapy: a Childrens Cancer Group randomized trial.

Authors:  B H Cohen; P M Zeltzer; J M Boyett; J R Geyer; J C Allen; J L Finlay; P McGuire-Cullen; J M Milstein; L B Rorke; P Stanley
Journal:  J Clin Oncol       Date:  1995-07       Impact factor: 44.544

10.  Long time to diagnosis of medulloblastoma in children is not associated with decreased survival or with worse neurological outcome.

Authors:  Jean-Francois Brasme; Jacques Grill; Francois Doz; Brigitte Lacour; Dominique Valteau-Couanet; Stephan Gaillard; Olivier Delalande; Nozar Aghakhani; Stéphanie Puget; Martin Chalumeau
Journal:  PLoS One       Date:  2012-04-02       Impact factor: 3.240

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  3 in total

1.  Patterns, treatments, and outcomes of pediatric central nervous system tumors in Sudan: a single institution experience.

Authors:  M Mohammed Ali Elhassan; A Abdalla Mohamedani; H Hussein Mohammed Osman; N Osman Yousif; N Mohamed Elhaj; I Qaddoumi
Journal:  Childs Nerv Syst       Date:  2019-01-04       Impact factor: 1.475

2.  Factors associated with delayed diagnosis among Filipino pediatric brain tumor patients: a retrospective review.

Authors:  Patricia C Orduña; Cheryl Anne P Lubaton-Sacro
Journal:  CNS Oncol       Date:  2022-06-09

3.  Presenting symptoms and time to diagnosis for Pediatric Central Nervous System Tumors in Qatar: a report from Pediatric Neuro-Oncology Service in Qatar.

Authors:  Ata U R Maaz; Tayseer Yousif; Ayman Saleh; Ian Pople; Khalid Al-Kharazi; Jehan Al-Rayahi; Naser Elkum; Muzaffar Malik
Journal:  Childs Nerv Syst       Date:  2020-07-24       Impact factor: 1.475

  3 in total

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