Literature DB >> 17413997

Intra-arterial drug delivery: a concise review.

Shailendra Joshi1, Charles W Emala, John Pile-Spellman.   

Abstract

The therapeutic potential of intra-arterial (IA) drug delivery to the brain has received limited attention in the last decade. In the 1980s, efforts to treat brain tumors with IA chemotherapy, the leading application of this technology, yielded modest results. Poor control of tissue drug concentrations and the potential risk of permanent neurologic injury further prevented the wider use of IA drugs. Yet, IA drugs were anecdotally used for treating a wide spectrum of brain diseases. Recent advances in endovascular technology and the increased safety of angiographic procedures now compel us to reevaluate IA drug delivery. This review describes the pharmacologic principles, applications, and pitfalls of IA drug delivery to the brain.

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Year:  2007        PMID: 17413997     DOI: 10.1097/ANA.0b013e318033da41

Source DB:  PubMed          Journal:  J Neurosurg Anesthesiol        ISSN: 0898-4921            Impact factor:   3.956


  9 in total

1.  Magnetically-enabled and MR-monitored selective brain tumor protein delivery in rats via magnetic nanocarriers.

Authors:  Beata Chertok; Allan E David; Victor C Yang
Journal:  Biomaterials       Date:  2011-05-31       Impact factor: 12.479

2.  Computational pharmacokinetic rationale for intra-arterial delivery to the brain.

Authors:  Johann N R Cooke; Jason A Ellis; Shaolie Hossain; Juliane Nguyen; Jeffrey N Bruce; Shailendra Joshi
Journal:  Drug Deliv Transl Res       Date:  2016-10       Impact factor: 4.617

3.  Brain tumor targeting of magnetic nanoparticles for potential drug delivery: effect of administration route and magnetic field topography.

Authors:  Beata Chertok; Allan E David; Victor C Yang
Journal:  J Control Release       Date:  2011-07-07       Impact factor: 9.776

4.  Polyethyleneimine-modified iron oxide nanoparticles for brain tumor drug delivery using magnetic targeting and intra-carotid administration.

Authors:  Beata Chertok; Allan E David; Victor C Yang
Journal:  Biomaterials       Date:  2010-05-21       Impact factor: 12.479

5.  Mechanical thrombectomy in a pediatric patient with sedation aided by contralateral intra-arterial propofol injection: feasibility in an extreme condition.

Authors:  Davide Simonato; Mario Ganau; Paolo Feltracco; Francesco Causin; Marina Munari; Andrea Bortolato
Journal:  Childs Nerv Syst       Date:  2020-08-27       Impact factor: 1.475

Review 6.  Intracarotid delivery of drugs: the potential and the pitfalls.

Authors:  Shailendra Joshi; Phillip M Meyers; Eugene Ornstein
Journal:  Anesthesiology       Date:  2008-09       Impact factor: 7.892

7.  PAMAM Dendrimers Cross the Blood-Brain Barrier When Administered through the Carotid Artery in C57BL/6J Mice.

Authors:  Bhairavi Srinageshwar; Sarah Peruzzaro; Melissa Andrews; Kayla Johnson; Allison Hietpas; Brittany Clark; Crystal McGuire; Eric Petersen; Jordyn Kippe; Andrew Stewart; Olivia Lossia; Abeer Al-Gharaibeh; Aaron Antcliff; Rebecca Culver; Douglas Swanson; Gary Dunbar; Ajit Sharma; Julien Rossignol
Journal:  Int J Mol Sci       Date:  2017-03-14       Impact factor: 5.923

Review 8.  Think Big, Start Small: How Nanomedicine Could Alleviate the Burden of Rare CNS Diseases.

Authors:  Abdelfattah Faouzi; Valérie Gaëlle Roullin
Journal:  Pharmaceuticals (Basel)       Date:  2021-01-30

9.  A Primeval Mechanism of Tolerance to Desiccation Based on Glycolic Acid Saves Neurons in Mammals from Ischemia by Reducing Intracellular Calcium-Mediated Excitotoxicity.

Authors:  Alexandra Chovsepian; Daniel Berchtold; Katarzyna Winek; Uta Mamrak; Inés Ramírez Álvarez; Yanina Dening; Dominika Golubczyk; Luis Weitbrecht; Claudia Dames; Marine Aillery; Celia Fernandez-Sanz; Zdzislaw Gajewski; Marianne Dieterich; Miroslaw Janowski; Peter Falkai; Piotr Walczak; Nikolaus Plesnila; Andreas Meisel; Francisco Pan-Montojo
Journal:  Adv Sci (Weinh)       Date:  2021-12-14       Impact factor: 16.806

  9 in total

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