INTRODUCTION: We present three consecutive patients with central neurocytoma in whom proton MRS demonstrated the presence of alanine. MATERIALS AND METHODS: Three patients in the age range 24 to 30 years underwent MRI and proton MRS using a 1.5-T system. MRS was performed with the multivoxel PRESS sequence. All three patients underwent surgery and the diagnosis of central neurocytoma was established by histopathological examination and immunostaining. RESULTS: With an echo time of 135 ms glycine, high choline, small NAA and alanine were observed in all three patients. CONCLUSION: Alanine may be observed in central neurocytomas as it is in meningiomas. Other spectral peaks such as those for glycine and NAA should help to identify this tumor correctly.
INTRODUCTION: We present three consecutive patients with central neurocytoma in whom proton MRS demonstrated the presence of alanine. MATERIALS AND METHODS: Three patients in the age range 24 to 30 years underwent MRI and proton MRS using a 1.5-T system. MRS was performed with the multivoxel PRESS sequence. All three patients underwent surgery and the diagnosis of central neurocytoma was established by histopathological examination and immunostaining. RESULTS: With an echo time of 135 ms glycine, high choline, small NAA and alanine were observed in all three patients. CONCLUSION:Alanine may be observed in central neurocytomas as it is in meningiomas. Other spectral peaks such as those for glycine and NAA should help to identify this tumor correctly.
Authors: C Majós; J Alonso; C Aguilera; M Serrallonga; S Coll; J J Acebes; C Arús; J Gili Journal: Neuroradiology Date: 2003-02-19 Impact factor: 2.804
Authors: P Demaerel; K Johannik; P Van Hecke; C Van Ongeval; S Verellen; G Marchal; G Wilms; C Plets; J Goffin; F Van Calenbergh Journal: J Comput Assist Tomogr Date: 1991 Jan-Feb Impact factor: 1.826