BACKGROUND & AIMS: A potential downside of colorectal cancer screening is that a "health certificate effect" might have negative effects on lifestyle. The aim of the present randomized controlled trial was to evaluate lifestyle changes in a group of individuals offered flexible sigmoidoscopy screening compared with a control group and also in relation to screening outcome. METHODS:Men and women aged 50-55 years were drawn by randomization from the population registry to be invited forflexible sigmoidoscopy screening (n = 6961) or not to be invited (n = 7000). Both groups were asked to fill in a questionnaire on selected lifestyle indicators at baseline and 3 years later. From both rounds, 3598 pairs of completed questionnaires were available for analysis from the screening group and 3462 from the control group. RESULTS: Both groups revealed a desirable change in most lifestyle indicators. A weight gain in the screening group was, on average, 0.24 kg higher than in the control group (P = .023). The screening group had poorer improvement in score for smoking (mean difference, 0.05; P = .013) and exercise habits (mean difference, -0.12; P = .001) and a lower increase in servings/day of fruit, berries, and vegetables (mean difference, -0.10; P = .001) compared with controls. The weight gain in screen-negative individuals (ie, no neoplasia) was, on average, 0.5 kg (P = .020) more than for screen positives. CONCLUSIONS: The present study has demonstrated a possible health certificate effect of flexible sigmoidoscopy screening and screening outcome on lifestyle. Although modest, these findings indicate a potential need for patient education in screening programs.
RCT Entities:
BACKGROUND & AIMS: A potential downside of colorectal cancer screening is that a "health certificate effect" might have negative effects on lifestyle. The aim of the present randomized controlled trial was to evaluate lifestyle changes in a group of individuals offered flexible sigmoidoscopy screening compared with a control group and also in relation to screening outcome. METHODS:Men and women aged 50-55 years were drawn by randomization from the population registry to be invited for flexible sigmoidoscopy screening (n = 6961) or not to be invited (n = 7000). Both groups were asked to fill in a questionnaire on selected lifestyle indicators at baseline and 3 years later. From both rounds, 3598 pairs of completed questionnaires were available for analysis from the screening group and 3462 from the control group. RESULTS: Both groups revealed a desirable change in most lifestyle indicators. A weight gain in the screening group was, on average, 0.24 kg higher than in the control group (P = .023). The screening group had poorer improvement in score for smoking (mean difference, 0.05; P = .013) and exercise habits (mean difference, -0.12; P = .001) and a lower increase in servings/day of fruit, berries, and vegetables (mean difference, -0.10; P = .001) compared with controls. The weight gain in screen-negative individuals (ie, no neoplasia) was, on average, 0.5 kg (P = .020) more than for screen positives. CONCLUSIONS: The present study has demonstrated a possible health certificate effect of flexible sigmoidoscopy screening and screening outcome on lifestyle. Although modest, these findings indicate a potential need for patient education in screening programs.
Authors: M F Kaminski; M Bretthauer; A G Zauber; E J Kuipers; H-O Adami; M van Ballegooijen; J Regula; M van Leerdam; T Stefansson; L Påhlman; E Dekker; M A Hernán; K Garborg; G Hoff Journal: Endoscopy Date: 2012-06-21 Impact factor: 10.093
Authors: C I Condurache; S Chiu; P Chotiyarnwong; H Johansson; L Shepstone; E Lenaghan; C Cooper; S Clarke; R F S Khioe; R Fordham; N Gittoes; I Harvey; N C Harvey; A Heawood; R Holland; A Howe; J A Kanis; T Marshall; T W O'Neill; T J Peters; N M Redmond; D Torgerson; D Turner; E McCloskey Journal: Osteoporos Int Date: 2020-01-20 Impact factor: 4.507
Authors: Gregory P Tarr; Andrew Crowley; Rhys John; Jonathan B Kok; Ho-Nam L Lee; Hasif Mustafa; Kia M Sii; Rebecca Smith; Sung-Eun Q Son; Lauren J Weaver; Claire Cameron; John D Dockerty; Michael Schultz; Iain A Murray Journal: BMC Gastroenterol Date: 2014-02-07 Impact factor: 3.067
Authors: Markus Dines Knudsen; Liang Wang; Kai Wang; Kana Wu; Shuji Ogino; Andrew T Chan; Edward Giovannucci; Mingyang Song Journal: Clin Gastroenterol Hepatol Date: 2021-07-10 Impact factor: 13.576