Literature DB >> 1736003

Surgical treatment of acute type A dissecting aneurysm, with preservation of the native aortic valve and use of biologic glue. Follow-up to 6 years.

E E Weinschelbaum1, C Schamun, V Caramutti, H Tacchi, J Cors, R G Favaloro.   

Abstract

We present an analysis of 59 patients operated on between 1983 and 1987 for acute type A dissecting aneurysm with aortic valve insufficiency. The ascending aorta was replaced with a Dacron tube, the layers of the dissection were unified with gelatin-resorcine-formaldehyde glue, and the natural aortic valve was preserved. Follow-up every 6 months was subject to actuarial analysis. The hospital mortality rate was 22%. The survivors were studied for 35.9 +/- 18.6 months (mean +/- standard deviation). Eight patients died (six of cardiovascular causes, one of cancer of the colon, and one of an unknown cause). Seventeen (36.9%) had aortic insufficiency, eight mild and nine moderate to severe. Four patients with severe insufficiency had reoperation with valve replacement. Excluding patients who have died or undergone reoperation, 29 of the remainder (90.6%) are free of symptoms. The follow-up survival rate is 61% +/- 6.93% (standard error) including hospital mortality. It is 55.4% +/- 7% (standard error) excluding reoperation and 44.2% +/- 7.1% (standard error) additionally excluding modest or severe aortic insufficiency. The use of gelatin-resorcine-formal glue allowed preservation of the native aortic valve, obviating the need for anticoagulants, and no embolic or hemorrhagic episodes were registered.

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Year:  1992        PMID: 1736003

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  6 in total

1.  Aortic stump tailoring with GRF glue and a felt strip.

Authors:  M Machii; T Sugimoto; K Sasaki; A Harada
Journal:  Surg Today       Date:  1999       Impact factor: 2.549

2.  Cyanoacrylate glue as an alternative to an additional suture line in the repair of type A aortic dissection.

Authors:  R De Paulis; S L Matteucci; A Penta de Peppo; L Chiariello
Journal:  Tex Heart Inst J       Date:  1999

Review 3.  An update on surgery for acute type A aortic dissection: aortic root repair, endovascular stent graft, and genetic research.

Authors:  Shinichi Suzuki; Munetaka Masuda
Journal:  Surg Today       Date:  2009-03-25       Impact factor: 2.549

4.  Effectiveness of a new inflatable balloon device for gluing dissected layers in an experimental model of aortic dissection.

Authors:  Necmettin Colak; Yunus Nazli; Mehmet Fatih Alpay; Ismail Olgun Akkaya; Omer Nuri Aksoy; Sukran Akgedik; Omer Cakir
Journal:  Exp Clin Cardiol       Date:  2013

Review 5.  The use of surgical glue in acute type A aortic dissection.

Authors:  Shinichi Suzuki; Munetaka Masuda; Kiyotaka Imoto
Journal:  Gen Thorac Cardiovasc Surg       Date:  2013-11-21

6.  When and how to replace the aortic root in type A aortic dissection.

Authors:  Bradley G Leshnower; Edward P Chen
Journal:  Ann Cardiothorac Surg       Date:  2016-07
  6 in total

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