BACKGROUND AND PURPOSE: The canine vein pouch aneurysm model is widely used for testing and development of devices directed at the endovascular treatment of aneurysms. Our purpose was to determine the incidence of spontaneous thrombosis and rupture of these aneurysms. MATERIALS AND METHODS: A retrospective review of laboratory records of canine vein pouch aneurysms made during a 6-year period was performed. The aneurysm and parent artery dimensions as well as incidences of spontaneous thrombosis and rupture were noted. RESULTS: During the interval studied, 326 vein patch aneurysms were made in 310 canines. Of these, 102 were sidewall (lateral) and 224 were bifurcation aneurysms. Spontaneous occlusion occurred in 9 of the sidewall aneurysms and in only 1 of the bifurcation aneurysms. None of the aneurysms ruptured. CONCLUSION: Spontaneous occlusion of the sidewall canine vein patch aneurysm occurred less than 10% of the time; in the bifurcation aneurysms, it almost never occurred. These characteristics enhance the value of this model for use in testing of devices intended for the endovascular treatment of aneurysms.
BACKGROUND AND PURPOSE: The canine vein pouch aneurysm model is widely used for testing and development of devices directed at the endovascular treatment of aneurysms. Our purpose was to determine the incidence of spontaneous thrombosis and rupture of these aneurysms. MATERIALS AND METHODS: A retrospective review of laboratory records of canine vein pouch aneurysms made during a 6-year period was performed. The aneurysm and parent artery dimensions as well as incidences of spontaneous thrombosis and rupture were noted. RESULTS: During the interval studied, 326 vein patch aneurysms were made in 310 canines. Of these, 102 were sidewall (lateral) and 224 were bifurcation aneurysms. Spontaneous occlusion occurred in 9 of the sidewall aneurysms and in only 1 of the bifurcation aneurysms. None of the aneurysms ruptured. CONCLUSION:Spontaneous occlusion of the sidewall canine vein patch aneurysm occurred less than 10% of the time; in the bifurcation aneurysms, it almost never occurred. These characteristics enhance the value of this model for use in testing of devices intended for the endovascular treatment of aneurysms.
Authors: Jingfeng Jiang; Charles Strother; Kevin Johnson; Sara Baker; Dan Consigny; Oliver Wieben; James Zagzebski Journal: Phys Med Biol Date: 2011-02-23 Impact factor: 3.609
Authors: Jingfeng Jiang; Kevin Johnson; Kristian Valen-Sendstad; Kent-Andre Mardal; Oliver Wieben; Charles Strother Journal: Med Phys Date: 2011-11 Impact factor: 4.071
Authors: J Raymond; T E Darsaut; M Kotowski; A Makoyeva; G Gevry; F Berthelet; I Salazkin Journal: AJNR Am J Neuroradiol Date: 2012-11-15 Impact factor: 3.825
Authors: Aquilla S Turk; Christopher M Luty; Victoria Carr-Brendel; Igor Polyakov; Dan Consigny; Julie Grinde; Rajat Mukherjee; Charles M Strother Journal: Neuroradiology Date: 2007-09-27 Impact factor: 2.804