PURPOSE: To investigate the hemodynamic characteristics of lateral carotid artery aneurysms in a canine model and to determine their influence on coils and balloons. MATERIALS AND METHODS: Forty aneurysms were created in fourteen dogs and their hemodynamic characteristics and influence on coils and balloons were evaluated with angiography and color Doppler pre- and postplacement. Twenty aneurysms were treated with coils, eight with balloons, and 12 aneurysms served as controls. RESULTS: The aneurysms demonstrated three distinct zones of flow: 1) an inflow zone entering at the distal aspect of the aneurysm ostium, 2) an outflow zone exiting at the proximal ostium, and 3) a central slow flow vortex. The inflow zone is a determining factor in the placement and stability of coils and balloons placed within the aneurysm and in the thrombosis of an aneurysm. The force of the inflow is considerable and can alter the shape of coils and displace both coils and balloons positioned within the aneurysm. CONCLUSIONS: Coils and balloons need to be of shapes and sizes that do not conform to the inflow and outflow zones. Filling the aneurysm and blocking or displacing the inflow zone can produce thrombosis of an aneurysm with preservation of the parent artery.
PURPOSE: To investigate the hemodynamic characteristics of lateral carotid artery aneurysms in a canine model and to determine their influence on coils and balloons. MATERIALS AND METHODS: Forty aneurysms were created in fourteen dogs and their hemodynamic characteristics and influence on coils and balloons were evaluated with angiography and color Doppler pre- and postplacement. Twenty aneurysms were treated with coils, eight with balloons, and 12 aneurysms served as controls. RESULTS: The aneurysms demonstrated three distinct zones of flow: 1) an inflow zone entering at the distal aspect of the aneurysm ostium, 2) an outflow zone exiting at the proximal ostium, and 3) a central slow flow vortex. The inflow zone is a determining factor in the placement and stability of coils and balloons placed within the aneurysm and in the thrombosis of an aneurysm. The force of the inflow is considerable and can alter the shape of coils and displace both coils and balloons positioned within the aneurysm. CONCLUSIONS: Coils and balloons need to be of shapes and sizes that do not conform to the inflow and outflow zones. Filling the aneurysm and blocking or displacing the inflow zone can produce thrombosis of an aneurysm with preservation of the parent artery.
Authors: Daying Dai; Yong Hong Ding; Mark A Danielson; Ramanathan Kadirvel; Debra A Lewis; Harry J Cloft; David F Kallmes Journal: AJNR Am J Neuroradiol Date: 2005 Nov-Dec Impact factor: 3.825
Authors: Chander Sadasivan; Baruch B Lieber; Matthew J Gounis; Demetrius K Lopes; L N Hopkins Journal: AJNR Am J Neuroradiol Date: 2002-08 Impact factor: 3.825
Authors: Stephan Meckel; Aurelien F Stalder; Francesco Santini; Ernst-Wilhelm Radü; Daniel A Rüfenacht; Michael Markl; Stephan G Wetzel Journal: Neuroradiology Date: 2008-03-19 Impact factor: 2.804
Authors: Timo Krings; Walter Möller-Hartmann; Franz-Josef Hans; Ruth Thiex; Anna Brunn; Kira Scherer; Alexander Meetz; Heiko Dreeskamp; Klaus-Peter Stein; Joachim M Gilsbach; Armin Thron Journal: Neuroradiology Date: 2003-05-28 Impact factor: 2.804