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Literature DB >> 17343408

Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice models.

Yun Zhou¹, Yun-Heng Shen, Chuan Zhang, Juan Su, Run-Hui Liu, Wei-Dong Zhang.

Abstract

Three new triterpene glycosides, bacopasides VI-VIII (1-3), together with three known analogues, bacopaside I (4), bacopaside II (5), and bacopasaponsin C (6), were isolated from the whole plant of Bacopa monnieri. Compounds 4, 5, and 6 showed antidepressant activity when tested on forced swimming and tail suspension in mice, respectively.

Entities: Chemical Disease Species

Mesh：

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Year: 2007 PMID： 17343408 DOI： 10.1021/np060470s

Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050

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Cited

12 in total

1. Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Authors: Bharat B Aggarwal; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadev; Byoungduck Park; Ji Hye Kim; Subash C Gupta; Kanokkarn Phromnoi; Chitra Sundaram; Seema Prasad; Madan M Chaturvedi; Bokyung Sung
Journal: Curr Drug Targets Date: 2011-10 Impact factor: 3.465

2. Antidepressant-like Effect of Bacopaside I in Mice Exposed to Chronic Unpredictable Mild Stress by Modulating the Hypothalamic-Pituitary-Adrenal Axis Function and Activating BDNF Signaling Pathway.

Authors: Xianpeng Zu; Mingjian Zhang; Wencai Li; Haisheng Xie; Zhang Lin; Niao Yang; Xinru Liu; Weidong Zhang
Journal: Neurochem Res Date: 2017-07-31 Impact factor: 3.996

3. Chemical structures of constituents from the whole plant of Bacopa monniera.

Authors: Tomoe Ohta; Seikou Nakamura; Souichi Nakashima; Yoshimi Oda; Takahiro Matsumoto; Masashi Fukaya; Mamiko Yano; Masayuki Yoshikawa; Hisashi Matsuda
Journal: J Nat Med Date: 2016-03-24 Impact factor: 2.343

4. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.

Authors: Carlo Calabrese; William L Gregory; Michael Leo; Dale Kraemer; Kerry Bone; Barry Oken
Journal: J Altern Complement Med Date: 2008-07 Impact factor: 2.579

5. Effect of soybean supplementation on the memory of alprazolam-induced amnesic mice.

Authors: Nitin Bansal; Milind Parle
Journal: J Pharm Bioallied Sci Date: 2010-04

6. Antidepressive-Like Property of Dichloromethane Fraction of Pimenta pseudocaryophyllus and Relevance of Monoamine Metabolic Enzymes.

Authors: James Oluwagbamigbe Fajemiroye; José Luís Rodrigues Martins; Paulo César Ghedini; Pablinny Morreira Galdino; Joelma Abadia Marciano de Paula; José Realino de Paula; Fabio Fagundes Da Rocha; Elson Alves Costa
Journal: Evid Based Complement Alternat Med Date: 2013-01-09 Impact factor: 2.629

Triterpene saponins from Bacopa monnieri and their antidepressant effects in two mice models.

1. Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

2. Antidepressant-like Effect of Bacopaside I in Mice Exposed to Chronic Unpredictable Mild Stress by Modulating the Hypothalamic-Pituitary-Adrenal Axis Function and Activating BDNF Signaling Pathway.

3. Chemical structures of constituents from the whole plant of Bacopa monniera.

4. Effects of a standardized Bacopa monnieri extract on cognitive performance, anxiety, and depression in the elderly: a randomized, double-blind, placebo-controlled trial.

5. Effect of soybean supplementation on the memory of alprazolam-induced amnesic mice.

6. Antidepressive-Like Property of Dichloromethane Fraction of Pimenta pseudocaryophyllus and Relevance of Monoamine Metabolic Enzymes.

7. Antidepressant-like effects of methanolic extract of Bacopa monniera in mice.

8. Antidepressant-like effects of a water-soluble extract from the culture medium of Ganoderma lucidum mycelia in rats.

9. Bacopaside I ameliorates cognitive impairment in APP/PS1 mice via immune-mediated clearance of β-amyloid.

Review 10. The Molecular Links of Re-Emerging Therapy: A Review of Evidence of Brahmi (Bacopa monniera).