| Literature DB >> 17270224 |
Luc Meva'a Mbaze1, Herve Martial P Poumale, Jean Duplex Wansi, Jean Alexandre Lado, Shamsun Nahar Khan, Muhammad Choudhary Iqbal, Bonaventure Tchaleu Ngadjui, Hartmut Laatsch.
Abstract
In addition to fatty acids, a mixture of sterols (beta-sitosterol, stigmasterol, campesterol and stigmastanol), lupeol, arctigenin methylether, sesamin, vanillic acid (1), 2,6-dimethoxy-1,4-benzoquinone (2), betulinic acid and two pentacyclic triterpene acetates were isolated from Fagara tessmannii Engl. They were identified as 3beta-acetoxy-16beta-hydroxybetulinic acid (3a) and 3beta,16beta-diacetoxybetulinic acid (3b), and their structures were established using 1 and 2D NMR spectra and by comparison with published data. Two derivatives of the compounds were prepared. Some isolated compounds were evaluated for their antifungal and antibacterial activities. Compounds 1 and 3a showed significant inhibition of alpha-glucosidase.Entities:
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Year: 2007 PMID： 17270224 DOI： 10.1016/j.phytochem.2006.12.015
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072