Literature DB >> 17269167

Embryonic-like stem cells from umbilical cord blood and potential for neural modeling.

Colin McGuckin1, Nicolas Forraz, Marc-Olivier Baradez, Christina Basford, Anne M Dickinson, Steve Navran, Jeffrey D Hartgerink.   

Abstract

Stem cells offer the distinct prospect of changing the face of human medicine. However, although they have potential to form different tissues, are still in the early stages of development as therapeutic interventions. The three most used stem cell sources are umbilical cord blood, bone marrow and human embryos. Whilst, cord blood is now used to treat over 70 disorders, at the time of writing this manuscript, not a single disease has been overcome or ameliorated using human embryonic stem cells. Advancing stem cell medicine requires ethically sound and scientifically robust models to develop tomorrow's medicines. Media attention, however, distracts from this reality; it is important to remember that stem cells are a new visitor to the medical world and require more research. Here we describe the utility of human cord blood to develop neural models that are necessary to take stem cells to the next level--into human therapies.

Entities:  

Mesh:

Year:  2006        PMID: 17269167

Source DB:  PubMed          Journal:  Acta Neurobiol Exp (Wars)        ISSN: 0065-1400            Impact factor:   1.579


  11 in total

1.  Ensheathing cell-conditioned medium directs the differentiation of human umbilical cord blood cells into aldynoglial phenotype cells.

Authors:  María Dolores Ponce-Regalado; Daniel Ortuño-Sahagún; Carlos Beas Zarate; Graciela Gudiño-Cabrera
Journal:  Hum Cell       Date:  2012-04-21       Impact factor: 4.174

Review 2.  [Stem cells--cloning, plasticity, bioethic].

Authors:  Pamina Pflegerl; Thomas Keller; Brigitte Hantusch; Thomas Sören Hoffmann; Lukas Kenner
Journal:  Wien Med Wochenschr       Date:  2008

Review 3.  An Overview on Human Umbilical Cord Blood Stem Cell-Based Alternative In Vitro Models for Developmental Neurotoxicity Assessment.

Authors:  Abhishek Kumar Singh; Mahendra Pratap Kashyap
Journal:  Mol Neurobiol       Date:  2015-06-04       Impact factor: 5.590

Review 4.  The umbilical cord: a rich and ethical stem cell source to advance regenerative medicine.

Authors:  N Forraz; C P McGuckin
Journal:  Cell Prolif       Date:  2011-04       Impact factor: 6.831

5.  Rotary suspension culture enhances mesendoderm differentiation of embryonic stem cells through modulation of Wnt/β-catenin pathway.

Authors:  Xiaohua Lei; Zhili Deng; Huishan Zhang; Huashan Zhao; Jiaxi Zhou; Shuang Liu; Qi Chen; Lina Ning; Yujing Cao; Xinyue Wang; Xudong Zhang; Enkui Duan
Journal:  Stem Cell Rev Rep       Date:  2014-08       Impact factor: 5.739

6.  The cord blood separation league table: a comparison of the major clinical grade harvesting techniques for cord blood stem cells.

Authors:  Christina Basford; Nicolas Forraz; Saba Habibollah; Kendal Hanger; Colin McGuckin
Journal:  Int J Stem Cells       Date:  2010-05       Impact factor: 2.500

7.  Stem cells for spinal cord regeneration: Current status.

Authors:  Zain A Sobani; Syed A Quadri; S Ather Enam
Journal:  Surg Neurol Int       Date:  2010-12-25

8.  Different Tissue-Derived Stem Cells: A Comparison of Neural Differentiation Capability.

Authors:  Gabriele Bonaventura; Sandrine Chamayou; Annalisa Liprino; Antonino Guglielmino; Michele Fichera; Massimo Caruso; Maria Luisa Barcellona
Journal:  PLoS One       Date:  2015-10-30       Impact factor: 3.240

Review 9.  Stem Cell Therapy: A New Treatment for Burns?

Authors:  Anna Arno; Alexandra H Smith; Patrick H Blit; Mohammed Al Shehab; Gerd G Gauglitz; Marc G Jeschke
Journal:  Pharmaceuticals (Basel)       Date:  2011-10-21

10.  Cord blood Lin(-)CD45(-) embryonic-like stem cells are a heterogeneous population that lack self-renewal capacity.

Authors:  Cesar Alvarez-Gonzalez; Richard Duggleby; Barbora Vagaska; Sergio Querol; Susana G Gomez; Patrizia Ferretti; Alejandro Madrigal
Journal:  PLoS One       Date:  2013-06-28       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.