Literature DB >> 21481046

The umbilical cord: a rich and ethical stem cell source to advance regenerative medicine.

N Forraz1, C P McGuckin.   

Abstract

Science and medicine place a lot of hope in the development of stem cell research and regenerative medicine. This review will define the concept of regenerative medicine and focus on an abundant stem cell source - neonatal tissues such as the umbilical cord. Umbilical cord blood has been used clinically for over 20 years as a cell source for haematopoietic stem cell transplantation. Beyond this, cord blood and umbilical cord-derived stem cells have demonstrated potential for pluripotent lineage differentiation (liver, pancreatic, neural tissues and more) in vitro and in vivo. This promising research has opened up a new era for utilization of neonatal stem cells, now used beyond haematology in clinical trials for autoimmune disorders, cerebral palsy or type I diabetes.
© 2011 Blackwell Publishing Ltd.

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Year:  2011        PMID： 21481046      PMCID： PMC6495455          DOI： 10.1111/j.1365-2184.2010.00729.x

Source DB:  PubMed          Journal:  Cell Prolif        ISSN： 0960-7722            Impact factor:   6.831


  82 in total

Review 1.  What is regenerative medicine? Emergence of applied stem cell and developmental biology.

Authors:  V Mironov; R P Visconti; R R Markwald
Journal:  Expert Opin Biol Ther       Date:  2004-06       Impact factor: 4.388

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Authors:  L R Kaiser
Journal:  Top Health Care Financ       Date:  1992

3.  Isolation, culture and characterisation of fibroblast-like cells derived from the Wharton's jelly portion of human umbilical cord.

Authors:  K D McElreavey; A I Irvine; K T Ennis; W H McLean
Journal:  Biochem Soc Trans       Date:  1991-02       Impact factor: 5.407

Review 4.  Umbilical cord blood: a unique source of pluripotent stem cells for regenerative medicine.

Authors:  David T Harris; Ian Rogers
Journal:  Curr Stem Cell Res Ther       Date:  2007-12       Impact factor: 3.828

5.  Long-term survival and characterisation of human umbilical cord-derived mesenchymal stem cells on dermal equivalents.

Authors:  Rebekka K Schneider; Andrea Püllen; Rafael Kramann; Jörg Bornemann; Ruth Knüchel; Sabine Neuss; Alberto Perez-Bouza
Journal:  Differentiation       Date:  2010-02-11       Impact factor: 3.880

6.  Hematopoietic reconstitution in a patient with Fanconi's anemia by means of umbilical-cord blood from an HLA-identical sibling.

Authors:  E Gluckman; H A Broxmeyer; A D Auerbach; H S Friedman; G W Douglas; A Devergie; H Esperou; D Thierry; G Socie; P Lehn
Journal:  N Engl J Med       Date:  1989-10-26       Impact factor: 91.245

Review 7.  Human umbilical cord blood as an emerging stem cell therapy for diabetes mellitus.

Authors:  Alluru S Reddi; Kishore Kuppasani; Norman Ende
Journal:  Curr Stem Cell Res Ther       Date:  2010-12       Impact factor: 3.828

8.  Umbilical cord stem cell seeding on fast-resorbable calcium phosphate bone cement.

Authors:  Hockin H K Xu; Liang Zhao; Michael S Detamore; Shozo Takagi; Laurence C Chow
Journal:  Tissue Eng Part A       Date:  2010-09       Impact factor: 3.845

9.  Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution.

Authors:  Colleen Delaney; Shelly Heimfeld; Carolyn Brashem-Stein; Howard Voorhies; Ronald L Manger; Irwin D Bernstein
Journal:  Nat Med       Date:  2010-01-17       Impact factor: 53.440

10.  Cord blood revelations: the importance of being a first born girl, big, on time and to a young mother!

Authors:  C P McGuckin; C Basford; K Hanger; S Habibollah; N Forraz
Journal:  Early Hum Dev       Date:  2007-10-17       Impact factor: 2.079
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  34 in total

Review 1.  An Overview on Human Umbilical Cord Blood Stem Cell-Based Alternative In Vitro Models for Developmental Neurotoxicity Assessment.

Authors:  Abhishek Kumar Singh; Mahendra Pratap Kashyap
Journal:  Mol Neurobiol       Date:  2015-06-04       Impact factor: 5.590

2.  Differentiation of Wharton's Jelly-Derived Mesenchymal Stem Cells into Motor Neuron-Like Cells on Three-Dimensional Collagen-Grafted Nanofibers.

Authors:  Zohreh Bagher; Mahmoud Azami; Somayeh Ebrahimi-Barough; Hamid Mirzadeh; Atefeh Solouk; Mansooreh Soleimani; Jafar Ai; Mohammad Reza Nourani; Mohammad Taghi Joghataei
Journal:  Mol Neurobiol       Date:  2015-05-24       Impact factor: 5.590

3.  Induction of human umbilical Wharton's jelly-derived mesenchymal stem cells toward motor neuron-like cells.

Authors:  Zohreh Bagher; Somayeh Ebrahimi-Barough; Mahmoud Azami; Hamid Mirzadeh; Mansooreh Soleimani; Jafar Ai; Mohammad Reza Nourani; Mohammad Taghi Joghataei
Journal:  In Vitro Cell Dev Biol Anim       Date:  2015-07-07       Impact factor: 2.416

Review 4.  Repairing neural injuries using human umbilical cord blood.

Authors:  Tao Sun; Quan-Hong Ma
Journal:  Mol Neurobiol       Date:  2012-12-30       Impact factor: 5.590

5.  Effects of telomerase activity and apoptosis on ex vivo expansion of cord blood CD34(+) cells.

Authors:  J Ge; H Cai; Q Li; Z Du; W S Tan
Journal:  Cell Prolif       Date:  2012-12-15       Impact factor: 6.831

6.  Role of cord blood and bone marrow mesenchymal stem cells in recent deep burn: a case-control prospective study.

Authors:  Wael Abo-Elkheir; Fawzy Hamza; Ahmed M Elmofty; Atef Emam; Magdy Abdl-Moktader; Sameh Elsherefy; Hala Gabr
Journal:  Am J Stem Cells       Date:  2017-10-01

Review 7.  Umbilical cord blood banking: an update.

Authors:  Merlin G Butler; Jay E Menitove
Journal:  J Assist Reprod Genet       Date:  2011-05-27       Impact factor: 3.412

8.  Extracellular regulated protein kinases 1/2 phosphorylation is required for hepatic differentiation of human umbilical cord-derived mesenchymal stem cells.

Authors:  Yongmin Yan; Yuan Zhu; Feng Sun; Bin Zhang; Limin Li; Zixuan Sun; Wei Li; Hui Qian; Wei Zhu; Wenrong Xu
Journal:  Exp Biol Med (Maywood)       Date:  2015-01-08

Review 9.  Stem cell therapy to cure type 1 diabetes: from hype to hope.

Authors:  Preeti Chhabra; Kenneth L Brayman
Journal:  Stem Cells Transl Med       Date:  2013-04-09       Impact factor: 6.940

10.  Comparison of Preterm and Term Wharton's Jelly-Derived Mesenchymal Stem Cell Properties in Different Oxygen Tensions.

Authors:  Saloni Balgi-Agarwal; Caitlyn Winter; Alexis Corral; Shamimunisa B Mustafa; Peter Hornsby; Alvaro Moreira
Journal:  Cells Tissues Organs       Date:  2018-06-27       Impact factor: 2.481
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