Literature DB >> 17263287

Elevated HIV seroprevalence and risk behavior among Ugandan TB suspects: implications for HIV testing and prevention.

P Srikantiah1, R Lin, M Walusimbi, A Okwera, H Luzze, C C Whalen, W H Boom, D V Havlir, E D Charlebois.   

Abstract

OBJECTIVES: Voluntary counseling and testing (VCT) for the human immunodeficiency virus (HIV) is recommended for persons treated for tuberculosis (TB). Opportunities to diagnose HIV may be missed by limiting HIV testing to only persons diagnosed with TB. Among TB suspects in Uganda, we determined HIV prevalence, risk behaviors, and willingness to refer family for VCT.
METHODS: Consenting adult patients presenting for evaluation at a referral TB clinic received same-day VCT. TB diagnosis data were abstracted from clinical records.
RESULTS: Among 665 eligible patients, 565 (85%) consented to VCT. Among these, 238 (42%) were HIV-positive. Of the HIV-infected patients, 37% had received a non-TB diagnosis. HIV seroprevalence was higher in patients with a non-TB diagnosis (49%) than those diagnosed with TB (39%) (P = 0.02). Fewer than 6% of HIV-infected patients reported always using condoms with sexual partners. The majority of patients (86%) reported being 'very willing' to refer family members for VCT.
CONCLUSIONS: Over 35% of HIV-infected cases in our population would have been undetected if HIV testing was limited to cases with diagnosed TB. The high HIV seroprevalence in both TB and non-TB cases merits HIV testing for all patients evaluated at TB clinics. HIV-infected TB suspects reporting high-risk behavior are at risk for HIV transmission, and should receive risk-reduction counseling.

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Year:  2007        PMID: 17263287      PMCID: PMC2846511     

Source DB:  PubMed          Journal:  Int J Tuberc Lung Dis        ISSN: 1027-3719            Impact factor:   2.373


  29 in total

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2.  Home-based model for HIV voluntary counselling and testing.

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Journal:  Lancet       Date:  2003-05-03       Impact factor: 79.321

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Journal:  Int J Tuberc Lung Dis       Date:  2003-12       Impact factor: 2.373

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Authors:  Kerstin E E Schroder; Michael P Carey; Peter A Vanable
Journal:  Ann Behav Med       Date:  2003-10

5.  Outcome of HIV-associated tuberculosis in the era of highly active antiretroviral therapy.

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6.  A clinical evaluation of children under the age of five years who are household contacts of adults with sputum positive tuberculosis in Harare, Zimbabwe.

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7.  Effect of an HIV counseling and testing program on AIDS-related knowledge and practices in tuberculosis clinics in Abidjan, Côte d'Ivoire.

Authors:  S Z Wiktor; L Abouya; H Angoran; J McFarland; M Sassan-Morokro; O Tossou; D Coulibaly; I M Coulibaly; A E Greenberg
Journal:  Int J Tuberc Lung Dis       Date:  2004-04       Impact factor: 2.373

8.  Does tuberculosis increase HIV load?

Authors:  John H Day; Alison D Grant; Katherine L Fielding; Lynn Morris; Victoria Moloi; Salome Charalambous; Adrian J Puren; Richard E Chaisson; Kevin M De Cock; Richard J Hayes; Gavin J Churchyard
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9.  Etiology of pulmonary infections in predominantly HIV-infected adults with suspected tuberculosis, Botswana.

Authors:  S Lockman; N Hone; T A Kenyon; M Mwasekaga; M Villauthapillai; T Creek; E Zell; A Kirby; W L Thacker; D Talkington; I N Moura; N J Binkin; L Clay; J W Tappero
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Authors:  Lynn Morris; Desmond J Martin; Helba Bredell; Stephina N Nyoka; Leonard Sacks; Stella Pendle; Liesl Page-Shipp; Christopher L Karp; Timothy R Sterling; Thomas C Quinn; Richard E Chaisson
Journal:  J Infect Dis       Date:  2003-06-04       Impact factor: 5.226

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  23 in total

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Journal:  Public Health Action       Date:  2013-09-21

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4.  Assessing the accessibility of HIV care packages among tuberculosis patients in the Northwest Region, Cameroon.

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5.  Low HIV testing rates among tuberculosis patients in Kampala, Uganda.

Authors:  Ibrahim Sendagire; Imke Schreuder; Mesach Mubiru; Maarten Schim van der Loeff; Frank Cobelens; Joseph Konde-Lule
Journal:  BMC Public Health       Date:  2010-03-31       Impact factor: 3.295

6.  Polymerase chain reaction of secA1 on sputum or oral wash samples for the diagnosis of pulmonary tuberculosis.

Authors:  J Lucian Davis; Laurence Huang; Joseph A Kovacs; Henry Masur; Patrick Murray; Diane V Havlir; William O Worodria; Edwin D Charlebois; Padmini Srikantiah; Adithya Cattamanchi; Charles Huber; Yvonne R Shea; Yuenwah Chow; Steven H Fischer
Journal:  Clin Infect Dis       Date:  2009-03-15       Impact factor: 9.079

7.  Characteristics and management of presumptive tuberculosis in public health facilities in Malawi, 2014-2016.

Authors:  W Ng'ambi; S Gugsa; H Tweya; B Girma; H Kanyerere; I Dambe; Y Babaye; J Mpunga; S Phiri
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8.  Are HIV-positive presumptive tuberculosis patients without tuberculosis getting the care they need in Zimbabwe?

Authors:  R A Dlodlo; Z E Hwalima; S Sithole; K C Takarinda; K Tayler-Smith; A D Harries
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9.  The whole is greater than the sum of the parts: recognising missed opportunities for an optimal response to the rapidly maturing TB-HIV co-epidemic in South Africa.

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Journal:  BMC Public Health       Date:  2009-07-16       Impact factor: 3.295

10.  Feasibility and effectiveness of provider initiated HIV testing and counseling of TB suspects in Vizianagaram district, South India.

Authors:  Shanta Achanta; Ajay M V Kumar; Sharath Burugina Nagaraja; Jyoti Jaju; Srinivas Rao Motta Shamrao; Ramakrishna Uppaluri; Rama Rao Tekumalla; Devesh Gupta; Ashok Kumar; Srinath Satyanarayana; Puneet K Dewan
Journal:  PLoS One       Date:  2012-07-23       Impact factor: 3.240

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