Literature DB >> 17258508

Petri net based model of the body iron homeostasis.

Dorota Formanowicz1, Andrea Sackmann, Piotr Formanowicz, Jacek Błazewicz.   

Abstract

The body iron homeostasis is a not fully understood complex process. Despite the fact that some components of this process have been described in the literature, the complete model of the whole process has not been proposed. In this paper a Petri net based model of the body iron homeostasis is presented. Recently, Petri nets have been used for describing and analyzing various biological processes since they allow modeling the system under consideration very precisely. The main result presented in the paper is twofold, i.e., an informal description of the main part of the whole iron homeostasis process is described, and then it is also formulated in the formal language of Petri net theory. This model allows for a possible simulation of the process, since Petri net theory provides a lot of established analysis techniques.

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Year:  2006        PMID: 17258508     DOI: 10.1016/j.jbi.2006.12.001

Source DB:  PubMed          Journal:  J Biomed Inform        ISSN: 1532-0464            Impact factor:   6.317


  8 in total

1.  Some aspects of the anemia of chronic disorders modeled and analyzed by petri net based approach.

Authors:  Dorota Formanowicz; Andrea Sackmann; Adam Kozak; Jacek Błażewicz; Piotr Formanowicz
Journal:  Bioprocess Biosyst Eng       Date:  2011-01-08       Impact factor: 3.210

Review 2.  A systems biology approach to iron metabolism.

Authors:  Julia Chifman; Reinhard Laubenbacher; Suzy V Torti
Journal:  Adv Exp Med Biol       Date:  2014       Impact factor: 2.622

3.  Transferrin changes in haemodialysed patients.

Authors:  Dorota Formanowicz; Piotr Formanowicz
Journal:  Int Urol Nephrol       Date:  2011-04-01       Impact factor: 2.370

4.  A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress.

Authors:  Fiona Achcar; Jean-Michel Camadro; Denis Mestivier
Journal:  BMC Syst Biol       Date:  2011-04-13

5.  Modelling and analysis of the feeding regimen induced entrainment of hepatocyte circadian oscillators using petri nets.

Authors:  Samar Hayat Khan Tareen; Jamil Ahmad
Journal:  PLoS One       Date:  2015-03-19       Impact factor: 3.240

6.  Activated Oncogenic Pathway Modifies Iron Network in Breast Epithelial Cells: A Dynamic Modeling Perspective.

Authors:  Julia Chifman; Seda Arat; Zhiyong Deng; Erica Lemler; James C Pino; Leonard A Harris; Michael A Kochen; Carlos F Lopez; Steven A Akman; Frank M Torti; Suzy V Torti; Reinhard Laubenbacher
Journal:  PLoS Comput Biol       Date:  2017-02-06       Impact factor: 4.475

7.  Mathematical modeling of the molecular switch of TNFR1-mediated signaling pathways applying Petri net formalism and in silico knockout analysis.

Authors:  Leonie K Amstein; Jörg Ackermann; Jennifer Hannig; Ivan Đikić; Simone Fulda; Ina Koch
Journal:  PLoS Comput Biol       Date:  2022-08-22       Impact factor: 4.779

8.  Modeling and analysis of the impacts of jet lag on circadian rhythm and its role in tumor growth.

Authors:  Azka Hassan; Hufsah Ashraf; Amjad Ali; Jamil Ahmad
Journal:  PeerJ       Date:  2018-06-06       Impact factor: 2.984

  8 in total

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