BACKGROUND: Commonly used perioperative measurements of hemodynamics, such as Swan-Ganz catheter assessment, are invasive and may not be reliable under pneumoperitoneum. The purpose of this study was to validate the use of esophageal Doppler for noninvasive hemodynamic monitoring under pneumoperitoneum in an experimental pig model. METHODS: Eight female pigs were submitted to two 30-min study periods, one each for the baseline (no interventions) and pneumoperitoneum (12-mmHg carbon dioxide pneumoperitoneum) conditions. One pig was excluded because of tachycardia (>140 at baseline). A Swan-Ganz pulmonary artery catheter was used to measure cardiac output (CO-SG) and pulmonary capillary wedge pressure (PCWP). An esophageal Doppler probe was inserted to record cardiac output (CO-ED) and corrected flow time (FTc), an index of preload. Transthoracic echocardiography was used to measure left ventricular end-diastolic diameter (LVEDD) and cardiac output (CO-TTE). Pearson correlation was used to assess individual associations between the measured hemodynamic parameters. RESULTS: There was good correlation between CO-ED and CO-SG (r = 0.577; p < 0.001) and excellent correlation between CO-ED and CO-TTE (r = 0.815; p < 0.001). There was no correlation between FTc and LVEDD or PCWP. These relationships were consistent when analyzed separately at baseline and during pneumoperitoneum. CONCLUSION: Esophageal Doppler monitoring is a valid noninvasive method of estimating cardiac output at baseline and during pneumoperitoneum in a porcine model. Corrected flow time did not correlate with other estimates of preload at baseline or during pneumoperitoneum.
BACKGROUND: Commonly used perioperative measurements of hemodynamics, such as Swan-Ganz catheter assessment, are invasive and may not be reliable under pneumoperitoneum. The purpose of this study was to validate the use of esophageal Doppler for noninvasive hemodynamic monitoring under pneumoperitoneum in an experimental pig model. METHODS: Eight female pigs were submitted to two 30-min study periods, one each for the baseline (no interventions) and pneumoperitoneum (12-mmHg carbon dioxide pneumoperitoneum) conditions. One pig was excluded because of tachycardia (>140 at baseline). A Swan-Ganz pulmonary artery catheter was used to measure cardiac output (CO-SG) and pulmonary capillary wedge pressure (PCWP). An esophageal Doppler probe was inserted to record cardiac output (CO-ED) and corrected flow time (FTc), an index of preload. Transthoracic echocardiography was used to measure left ventricular end-diastolic diameter (LVEDD) and cardiac output (CO-TTE). Pearson correlation was used to assess individual associations between the measured hemodynamic parameters. RESULTS: There was good correlation between CO-ED and CO-SG (r = 0.577; p < 0.001) and excellent correlation between CO-ED and CO-TTE (r = 0.815; p < 0.001). There was no correlation between FTc and LVEDD or PCWP. These relationships were consistent when analyzed separately at baseline and during pneumoperitoneum. CONCLUSION: Esophageal Doppler monitoring is a valid noninvasive method of estimating cardiac output at baseline and during pneumoperitoneum in a porcine model. Corrected flow time did not correlate with other estimates of preload at baseline or during pneumoperitoneum.
Authors: James Dean Sandham; Russell Douglas Hull; Rollin Frederick Brant; Linda Knox; Graham Frederick Pineo; Christopher J Doig; Denny P Laporta; Sidney Viner; Louise Passerini; Hugh Devitt; Ann Kirby; Michael Jacka Journal: N Engl J Med Date: 2003-01-02 Impact factor: 91.245