Literature DB >> 17227002

Synthesis of potent bicyclic bisarylimidazole c-Jun N-terminal kinase inhibitors by catalytic C-H bond activation.

Jason C Rech1, Michihisa Yato, Derek Duckett, Brian Ember, Philip V LoGrasso, Robert G Bergman, Jonathan A Ellman.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17227002      PMCID： PMC2556147          DOI： 10.1021/ja0676004

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


× No keyword cloud information.
  6 in total

1.  Annulation of alkenyl-substituted heterocycles via rhodium-catalyzed intramolecular C-H activated coupling reactions.

Authors:  K L Tan; R G Bergman; J A Ellman
Journal:  J Am Chem Soc       Date:  2001-03-21       Impact factor: 15.419

2.  The neuroprotective action of JNK3 inhibitors based on the 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole scaffold.

Authors:  Piotr P Graczyk; Afzal Khan; Gurpreet S Bhatia; Vanessa Palmer; Darren Medland; Hirotoshi Numata; Hitoshi Oinuma; Jacqueline Catchick; Angela Dunne; Moira Ellis; Caroline Smales; Jonathan Whitfield; Stephen J Neame; Bina Shah; Daniel Wilton; Louise Morgan; Toshal Patel; Raymond Chung; Howard Desmond; James M Staddon; Nobuaki Sato; Atsushi Inoue
Journal:  Bioorg Med Chem Lett       Date:  2005-11-01       Impact factor: 2.823

3.  Asymmetric synthesis of protected 1,2-amino alcohols using tert-butanesulfinyl aldimines and ketimines.

Authors:  T P Tang; S K Volkman; J A Ellman
Journal:  J Org Chem       Date:  2001-12-28       Impact factor: 4.354

4.  An investigation of imidazole and oxazole syntheses using aryl-substituted TosMIC reagents.

Authors:  J Sisko; A J Kassick; M Mellinger; J J Filan; A Allen; M A Olsen
Journal:  J Org Chem       Date:  2000-03-10       Impact factor: 4.354

5.  Total syntheses of variolin B and deoxyvariolin B.

Authors:  Abderaouf Ahaidar; David Fernández; Gerardo Danelón; Carmen Cuevas; Ignacio Manzanares; Fernando Albericio; John A Joule; Mercedes Alvarez
Journal:  J Org Chem       Date:  2003-12-26       Impact factor: 4.354

6.  Experimental and computational studies on the mechanism of N-heterocycle C-H activation by Rh(I).

Authors:  Sean H Wiedemann; Jared C Lewis; Jonathan A Ellman; Robert G Bergman
Journal:  J Am Chem Soc       Date:  2006-02-22       Impact factor: 15.419
  6 in total
  8 in total

1.  Mechanistically driven development of iridium catalysts for asymmetric allylic substitution.

Authors:  John F Hartwig; Levi M Stanley
Journal:  Acc Chem Res       Date:  2010-09-28       Impact factor: 22.384

2.  Synthesis of multicyclic pyridine and quinoline derivatives via intramolecular C-H bond functionalization.

Authors:  Sirilata Yotphan; Robert G Bergman; Jonathan A Ellman
Journal:  Org Lett       Date:  2010-07-02       Impact factor: 6.005

3.  A mild and efficient approach to enantioenriched α-hydroxyethyl α,β-unsaturated δ-lactams.

Authors:  Seo-Jung Han; Brian M Stoltz
Journal:  Tetrahedron Lett       Date:  2016-05-25       Impact factor: 2.415

Review 4.  Direct functionalization of nitrogen heterocycles via Rh-catalyzed C-H bond activation.

Authors:  Jared C Lewis; Robert G Bergman; Jonathan A Ellman
Journal:  Acc Chem Res       Date:  2008-07-11       Impact factor: 22.384

5.  Regio- and enantioselective N-allylations of imidazole, benzimidazole, and purine heterocycles catalyzed by single-component metallacyclic iridium complexes.

Authors:  Levi M Stanley; John F Hartwig
Journal:  J Am Chem Soc       Date:  2009-07-01       Impact factor: 15.419

Review 6.  Rhodium-catalyzed C-C bond formation via heteroatom-directed C-H bond activation.

Authors:  Denise A Colby; Robert G Bergman; Jonathan A Ellman
Journal:  Chem Rev       Date:  2010-02-10       Impact factor: 60.622

7.  Rh(I)-bisphosphine-catalyzed asymmetric, intermolecular hydroheteroarylation of α-substituted acrylate derivatives.

Authors:  Claire M Filloux; Tomislav Rovis
Journal:  J Am Chem Soc       Date:  2014-12-29       Impact factor: 15.419

8.  Synthesis of skeletally diverse alkaloid-like molecules: exploitation of metathesis substrates assembled from triplets of building blocks.

Authors:  Sushil K Maurya; Mark Dow; Stuart Warriner; Adam Nelson
Journal:  Beilstein J Org Chem       Date:  2013-04-22       Impact factor: 2.883
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.