| Literature DB >> 14682696 |
Abderaouf Ahaidar1, David Fernández, Gerardo Danelón, Carmen Cuevas, Ignacio Manzanares, Fernando Albericio, John A Joule, Mercedes Alvarez.
Abstract
Two alternative synthetic routes have been developed for the preparation of variolin B and deoxyvariolin B. The strategy is based on the preparation of the core tricyclic ring common to all variolins, pyrido[3',2':4,5]pyrrolo[1,2-c]pyrimidine, followed by a palladium-catalyzed cross-coupling reaction to give the tetracyclic system.Entities:
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Year: 2003 PMID： 14682696 DOI： 10.1021/jo035332b
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354