| Literature DB >> 17191245 |
Walter R T Witschey1, Arijitt Borthakur, Mark A Elliott, Eric Mellon, Sampreet Niyogi, Chenyang Wang, Ravinder Reddy.
Abstract
The origin of image artifacts in an off-resonance spin-locking experiment is shown to be imperfections in the excitation flip angle. A pulse sequence for off-resonance spin locking is implemented that compensates for imperfections in the excitation flip angle through an off-resonance rotary echo. The off-resonance rotary echo alternates the frequency offset and phase of the RF transmitter during two spin-locking pulses of equal duration. The underlying theory is detailed, and MR images demonstrate the effectiveness of the technique in agarose gel phantoms and in in vivo human brain at 3T.Entities:
Mesh:
Year: 2007 PMID: 17191245 PMCID: PMC2877388 DOI: 10.1002/mrm.21134
Source DB: PubMed Journal: Magn Reson Med ISSN: 0740-3194 Impact factor: 4.668