Literature DB >> 17179348

ECG-gated 64-MDCT angiography in the differential diagnosis of acute chest pain.

Thorsten R C Johnson1, Konstantin Nikolaou, Bernd J Wintersperger, Andreas Knez, Peter Boekstegers, Maximilian F Reiser, Christoph R Becker.   

Abstract

OBJECTIVE: The most important differential diagnoses of acute chest pain include myocardial infarction, aortic dissection, and pulmonary embolism. The purpose of this study was to evaluate the diagnostic value of an ECG-gated 64-MDCT angiography protocol for simultaneous assessment of the pulmonary arteries, coronary arteries, and aorta within a single breath-hold. SUBJECTS AND METHODS: In 55 patients with acute chest pain, ECG-gated CT angiography was performed with a CT system in which 64 slices per gantry rotation were acquired. Density measurement and visual assessment of motion artifacts were performed to evaluate image quality. CT findings were correlated with results of laboratory tests and clinical follow-up. For 20 patients, two independent blinded reviewers compared findings on CT angiography with those on X-ray coronary angiography.
RESULTS: Adequate contrast enhancement of the pulmonary vessels, coronary arteries, and aorta was achieved in all cases. Regarding image quality of the coronary arteries, there was minor blurring in seven patients, and in one examination the images did not provide enough information for diagnosis. The average image quality rating was 1.2 on a scale in which 1 indicated no artifacts; 2, minor motion artifacts; and 3, image insufficient for diagnosis. The cause of chest pain was correctly identified with MDCT in 37 patients. The diagnoses included pulmonary embolism (n = 10), coronary stenosis (n = 9), and aortic dissection (n = 1). In four patients, additional diagnoses were found with other examinations.
CONCLUSION: With current techniques, ECG-gated CT angiography of the entire chest has very good image quality. The protocol proved helpful in the differential diagnosis of acute chest pain.

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Year:  2007        PMID: 17179348     DOI: 10.2214/AJR.05.1153

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  25 in total

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Authors:  Carsten Rist; T R Johnson; A Becker; A W Leber; A Huber; S Busch; C R Becker; M F Reiser; K Nikolaou
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Authors:  Patrick A Hein; Valentina C Romano; Alexander Lembcke; Juliane May; Patrik Rogalla
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Review 6.  Noninvasive cardiac imaging in suspected acute coronary syndrome.

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Review 8.  Cardiac CT in the emergency department: convincing evidence, but cautious implementation.

Authors:  Ricardo C Cury; Gudrun Feuchtner; Carol Mascioli; Jonathon Fialkow; Paul Andrulonis; Tomas Villanueva; Constantino S Pena; Warren R Janowitz; Barry T Katzen; Jack A Ziffer
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Review 9.  Coronary CT angiography in emergency department patients with acute chest pain: triple rule-out protocol versus dedicated coronary CT angiography.

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Review 10.  Acute chest pain imaging in the emergency department with cardiac computed tomography angiography.

Authors:  Ricardo C Cury; Gudrun Feutchner; Constantino S Pena; Warren R Janowitz; Barry T Katzen; Jack A Ziffer
Journal:  J Nucl Cardiol       Date:  2008 Jul-Aug       Impact factor: 5.952

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