Literature DB >> 1716616

Prevention of murine cerebral malaria by a stable prostacyclin analog.

K Sliwa1, H J Grundmann, S Neifer, M F Chaves, G Sahlmüller, E Blitstein-Willinger, U Bienzle, P G Kremsner.   

Abstract

Iloprost, a synthetic prostacyclin analog, successfully prevents the development of cerebral malaria in mice. Malaria antigen-induced tumor necrosis factor (TNF) production could be inhibited by iloprost in vitro and in vivo. Northern analysis of TNF mRNA revealed that malaria antigen-induced TNF expression was suppressed at the transcription level.

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Year:  1991        PMID： 1716616      PMCID： PMC258963          DOI： 10.1128/iai.59.10.3846-3848.1991

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  13 in total

Review 1.  Tumor-necrosis factor and other cytokines in cerebral malaria: experimental and clinical data.

Authors:  G E Grau; P F Piguet; P Vassalli; P H Lambert
Journal:  Immunol Rev       Date:  1989-12       Impact factor: 12.988

2.  Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction.

Authors:  P Chomczynski; N Sacchi
Journal:  Anal Biochem       Date:  1987-04       Impact factor: 3.365

3.  Specificity of in vivo tumor rejection assessed by mixing immune spleen cells with target and unrelated tumor cells.

Authors:  M Röllinghoff; N L Warner
Journal:  Proc Soc Exp Biol Med       Date:  1973-12

4.  Prostacyclin in Falciparum malaria.

Authors:  M J Weston; N Jackman; C Rudge; J Bowles; C Brady; C Bielawska; J O'Grady
Journal:  Lancet       Date:  1982-09-11       Impact factor: 79.321

5.  Fibrinolytic activity of 6-keto-prostaglandin E1.

Authors:  R Korbut; A Byrska-Danek; R J Gryglewski
Journal:  Thromb Haemost       Date:  1983-12-30       Impact factor: 5.249

6.  Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor.

Authors:  G E Grau; H Heremans; P F Piguet; P Pointaire; P H Lambert; A Billiau; P Vassalli
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

7.  Malarial parasites induce TNF production by macrophages.

Authors:  C A Bate; J Taverne; J H Playfair
Journal:  Immunology       Date:  1988-06       Impact factor: 7.397

Review 8.  Roles of tumour necrosis factor in the illness and pathology of malaria.

Authors:  I A Clark; G Chaudhri; W B Cowden
Journal:  Trans R Soc Trop Med Hyg       Date:  1989 Jul-Aug       Impact factor: 2.184

9.  TNF concentration in fatal cerebral, non-fatal cerebral, and uncomplicated Plasmodium falciparum malaria.

Authors:  D Kwiatkowski; A V Hill; I Sambou; P Twumasi; J Castracane; K R Manogue; A Cerami; D R Brewster; B M Greenwood
Journal:  Lancet       Date:  1990-11-17       Impact factor: 79.321

10.  Iloprost inhibits neutrophil function in vitro and in vivo and limits experimental infarct size in canine heart.

Authors:  P J Simpson; J Mickelson; J C Fantone; K P Gallagher; B R Lucchesi
Journal:  Circ Res       Date:  1987-05       Impact factor: 17.367
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  2 in total

1.  Malaria antigen and cytokine-induced production of reactive nitrogen intermediates by murine macrophages: no relevance to the development of experimental cerebral malaria.

Authors:  P G Kremsner; A Nüssler; S Neifer; M F Chaves; U Bienzle; G Senaldi; G E Grau
Journal:  Immunology       Date:  1993-02       Impact factor: 7.397

2.  Production of interleukin-6 by human and murine mononuclear leukocytes stimulated with Plasmodium antigens is enhanced by pentoxifylline, and tumor necrosis factor secretion is reduced.

Authors:  J Prada; C Prager; S Neifer; U Bienzle; P G Kremsner
Journal:  Infect Immun       Date:  1993-06       Impact factor: 3.441
  2 in total

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