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Literature DB >> 17165714

Contrasting views of the internal dynamics of the HhaI methyltransferase target DNA reported by solution and solid-state NMR spectroscopy.

Paul A Miller¹, Zahra Shajani, Gary A Meints, Dorothy Caplow, Gil Goobes, Gabriele Varani, Gary P Drobny.

Abstract

Solution and solid-state NMR have been used conjointly to probe the internal motions of a DNA dodecamer containing the recognition site for the HhaI methyltransferase. The results strongly suggest that ns-mus motions contribute to the functionally relevant dynamic properties of nucleic acids during DNA methylation.

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Year: 2006 PMID： 17165714 DOI： 10.1021/ja066329n

Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419

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Cited

7 in total

Review 1. Structural dynamics of bio-macromolecules by NMR: the slowly relaxing local structure approach.

Authors: Eva Meirovitch; Yury E Shapiro; Antonino Polimeno; Jack H Freed
Journal: Prog Nucl Magn Reson Spectrosc Date: 2010-05 Impact factor: 9.795

2. Solid-state deuterium NMR studies reveal micros-ns motions in the HIV-1 transactivation response RNA recognition site.

Authors: Greg L Olsen; Dorothy C Echodu; Zahra Shajani; Michael F Bardaro; Gabriele Varani; Gary P Drobny
Journal: J Am Chem Soc Date: 2008-02-15 Impact factor: 15.419

3. Extensive backbone dynamics in the GCAA RNA tetraloop analyzed using 13C NMR spin relaxation and specific isotope labeling.

Authors: James E Johnson; Charles G Hoogstraten
Journal: J Am Chem Soc Date: 2008-12-10 Impact factor: 15.419

Contrasting views of the internal dynamics of the HhaI methyltransferase target DNA reported by solution and solid-state NMR spectroscopy.

Review 1. Structural dynamics of bio-macromolecules by NMR: the slowly relaxing local structure approach.

2. Solid-state deuterium NMR studies reveal micros-ns motions in the HIV-1 transactivation response RNA recognition site.

3. Extensive backbone dynamics in the GCAA RNA tetraloop analyzed using 13C NMR spin relaxation and specific isotope labeling.

Review 4. Domain-elongation NMR spectroscopy yields new insights into RNA dynamics and adaptive recognition.

5. Solid state 2H NMR analysis of furanose ring dynamics in DNA containing uracil.

6. Furanose dynamics in the HhaI methyltransferase target DNA studied by solution and solid-state NMR relaxation.

7. Energy Landscapes for Base-Flipping in a Model DNA Duplex.